Kessl, Jacques J.

Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation

Jurado, K. A., Wang, H., Slaughter, A., Feng, L., Kessl, J. J., Koh, Y., Wang, W., Ballandras-Colas, A., Patel, P. A., Fuchs, J. R., et al. (2013) · Proceedings of the National Academy of Sciences

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 203

BET proteins promote efficient murine leukemia virus integration at transcription start sites

Sharma, A., Larue, R. C., Plumb, M. R., Malani, N., Male, F., Slaughter, A., Kessl, J. J., Shkriabai, N., Coward, E., Aiyer, S. S., et al. (2013) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchProtein Degradation and Inhibitors

Cited by 193

Molecular Basis for Atovaquone Binding to the Cytochrome bc 1 Complex

Kessl, J. J., Lange, B. B., Merbitz-Zahradnik, T., Zwicker, K., Hill, P., Meunier, B., Pálsdóttir, H., Hunte, C., Meshnick, S., & Trumpower, B. L. (2003) · Journal of Biological Chemistry

Photosynthetic Processes and MechanismsMitochondrial Function and Pathology

Cited by 160

HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis

Kessl, J. J., Kutluay, S. B., Townsend, D., Rebensburg, S., Slaughter, A., Larue, R. C., Shkriabai, N., Bakouche, N., Fuchs, J. R., Bieniasz, P. D., et al. (2016) · Cell

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 152

A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase

Sharma, A., Slaughter, A., Jena, N., Feng, L., Kessl, J. J., Fadel, H. J., Malani, N., Male, F., Wu, L., Poeschla, E., et al. (2014) · PLoS Pathogens

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 124

Recapitulation in Saccharomyces cerevisiae of Cytochrome b Mutations Conferring Resistance to Atovaquone in Pneumocystis jiroveci

Hill, P., Kessl, J., Fisher, N., Meshnick, S., Trumpower, B. L., & Meunier, B. (2003) · Antimicrobial Agents and Chemotherapy

Pneumocystis jirovecii pneumonia detection and treatmentFungal Plant Pathogen Control

Cited by 68

An Allosteric Mechanism for Inhibiting HIV-1 Integrase with a Small Molecule

Kessl, J. J., Eidahl, J. O., Shkriabai, N., Zhao, Z., McKee, C. J., Hess, S., Burke, T. R., & Kvaratskhelia, M. (2009) · Molecular Pharmacology

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 50

The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency

Feng, L., Dharmarajan, V., Serrao, E., Hoyte, A., Larue, R. C., Slaughter, A., Sharma, A., Plumb, M. R., Kessl, J. J., Fuchs, J. R., et al. (2016) · ACS Chemical Biology

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 37

A Critical Role of the C-terminal Segment for Allosteric Inhibitor-induced Aberrant Multimerization of HIV-1 Integrase

Shkriabai, N., Dharmarajan, V., Slaughter, A., Kessl, J. J., Larue, R. C., Feng, L., Fuchs, J. R., Griffin, P. R., & Kvaratskhelia, M. (2014) · Journal of Biological Chemistry

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 30