Zhou, Zinan

Somatic genomic changes in single Alzheimer’s disease neurons

Miller, M. B., Huang, A. Y., Kim, J., Zhou, Z., Kirkham, S. L., Maury, E. A., Ziegenfuss, J. S., Reed, H. C., Neil, J. E., Rento, L., et al. (2022) · Nature

Alzheimer's disease research and treatmentsDNA Repair Mechanisms

Cited by 223

Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements

Luquette, L. J., Miller, M. B., Zhou, Z., Bohrson, C. L., Zhao, Y., Jin, H., Gulhan, D., Ganz, J., Bizzotto, S., Kirkham, S., et al. (2022) · Nature Genetics

Single-cell and spatial transcriptomicsCancer Genomics and Diagnostics

Cited by 108

Rates and Patterns of Clonal Oncogenic Mutations in the Normal Human Brain

Ganz, J., Maury, E. A., Becerra, B., Bizzotto, S., Doan, R. N., Kenny, C. J., Shin, T., Kim, J., Zhou, Z., Ligon, K. L., et al. (2022) · Cancer Discovery

Cancer Genomics and DiagnosticsGlioma Diagnosis and Treatment

Cited by 48

Somatic cancer driver mutations are enriched and associated with inflammatory states in Alzheimer’s disease microglia

Huang, A. Y., Zhou, Z., Talukdar, M., Miller, M. B., Chhouk, B., Enyenihi, L., Rosen, I., Stronge, E., Zhao, B., Kim, D., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory)

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 16

Somatic cancer variants enriched in Alzheimer’s disease microglia-like cells drive inflammatory and proliferative states

Huang, A. Y., Zhou, Z., Talukdar, M., Enyenihi, L., Miller, M. B., Chhouk, B., Rosen, I., Zheng, M., Zhou, M., Yang, A., et al. (2026) · Cell

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 15

Clonal Hematopoiesis Mutations Increase Risk of Alzheimer’s Disease with APOE ε3/ε3 Genotype

Choi, J., Park, K. S., Le Guen, Y., Park, J.-H., Zhou, Z., Enyenihi, L., Rosen, I., Choi, Y.-H., Walsh, C. A., Kim, J.-W., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory)

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 5