Gottifredi, Vanesa

Mitochondrial fusion is essential for steroid biosynthesis

Duarte, A., Poderoso, C., Cooke, M., Soria, G., Cornejo Maciel, F., Gottifredi, V., & Podestá, E. J. (2012) · PLoS ONE

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 149

p53 accumulates but is functionally impaired when DNA synthesis is blocked

Gottifredi, V., Shieh, S.-Y., Taya, Y., & Prives, C. (2001) · Proceedings of the National Academy of Sciences

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 147

CDK-Independent and PCNA-Dependent Functions of p21 in DNA Replication

Mansilla, S. F., De La Vega, M. B., Calzetta, N. L., Siri, S. O., & Gottifredi, V. (2020) · Genes

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 114

p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation

Soria, G., Speroni, J., Podhajcer, O. L., Prives, C., & Gottifredi, V. (2008) · Journal of Cell Science

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 94

Decreased p21 levels are required for efficient restart of DNA synthesis after S phase block

Gottifredi, V., McKinney, K., Poyurovsky, M. V., & Prives, C. (2004) · Journal of Biological Chemistry

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 76

Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome

Quinet, A., Vessoni, A. T., Rocha, C. R. R., Gottifredi, V., Biard, D., Sarasin, A., Menck, C. F. M., & Stary, A. (2014) · DNA Repair

DNA Repair MechanismsCarcinogens and Genotoxicity Assessment

Cited by 70

Predominant role of DNA polymerase eta and p53-dependent translesion synthesis in the survival of ultraviolet-irradiated human cells

Lerner, L. K., Francisco, G., Soltys, D. T., Rocha, C. R. R., Quinet, A., Vessoni, A. T., Castro, L. P., David, T. I. P., Bustos, S. O., Strauss, B. E., et al. (2017) · Nucleic Acids Research

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 53

UV-triggered p21 degradation facilitates damaged-DNA replication and preserves genomic stability

Mansilla, S. F., Soria, G., Vallerga, M. B., Habif, M., Martinez-Lopez, W., Prives, C., & Gottifredi, V. (2013) · Nucleic Acids Research

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 50

Cyclin Kinase-independent role of p21CDKN1A in the promotion of nascent DNA elongation in unstressed cells

Mansilla, S. F., Bertolin, A. P., Bergoglio, V., Pillaire, M.-J., González Besteiro, M. A., Luzzani, C., Miriuka, S. G., Cazaux, C., Hoffmann, J.-S., & Gottifredi, V. (2016) · eLife

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 43

The identification of translesion DNA synthesis regulators: Inhibitors in the spotlight

Bertolin, A. P., Mansilla, S. F., & Gottifredi, V. (2015) · DNA Repair

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 30

AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress

Villafañez, F., García, I. A., Carbajosa, S., Pansa, M. F., Mansilla, S., Llorens, M. C., Angiolini, V., Guantay, L., Jacobs, H., Madauss, K. P., et al. (2019) · Oncogene

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 30

Unscheduled MRE11 activity triggers cell death but not chromosome instability in polymerase eta-depleted cells subjected to UV irradiation

Federico, M. B., Siri, S. O., Calzetta, N. L., Paviolo, N. S., de la Vega, M. B., Martino, J., Campana, M. C., Wiesmüller, L., & Gottifredi, V. (2020) · Oncogene

DNA Repair MechanismsCell death mechanisms and regulation

Cited by 12