Safadi, Rifaat

Obeticholic acid for the treatment of non-alcoholic steatohepatitis: Interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial

Younossi, Z. M., Ratziu, V., Loomba, R., Rinella, M., Anstee, Q. M., Goodman, Z., Bedossa, P., Geier, A., Beckebaum, S., Newsome, P. N., et al. (2019) · The Lancet

Liver Disease Diagnosis and TreatmentLiver Diseases and Immunity

Cited by 1,277

Anti-Fibrotic Activity of NK Cells in Experimental Liver Injury Through Killing of Activated HSC

Melhem, A., Muhanna, N., Bishara, A., Alvarez, C. E., Ilan, Y., Bishara, T., Horani, A., Nassar, M., Friedman, S. L., & Safadi, R. (2006) · Journal of Hepatology

Liver physiology and pathologyImmune Cell Function and Interaction

Cited by 270

Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes

Safadi, R., Ohta, M., Alvarez, C. E., Fiel, M. I., Bansal, M., Mehal, W. Z., & Friedman, S. L. (2004) · Gastroenterology

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 239

Aramchol in patients with nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled phase 2b trial

Ratziu, V., de Guevara, L., Safadi, R., Poordad, F., Fuster, F., Flores-Figueroa, J., Arrese, M., Fracanzani, A. L., Ben Bashat, D., Lackner, K., et al. (2021) · Nature Medicine

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 222

NKp46-Mediated Killing of Human and Mouse Hepatic Stellate Cells Attenuates Liver Fibrosis

Gur, C., Doron, S., Kfir-Erenfeld, S., Horwitz, E., Abu-tair, L., Safadi, R., & Mandelboim, O. (2012) · Gut

Liver physiology and pathologyImmune Cell Function and Interaction

Cited by 173

Amelioration of hepatic fibrosis by NK cell activation

Muhanna, N., Tair, L. A., Doron, S., Amer, J., Azzeh, M., Mahamid, M., Friedman, S., & Safadi, R. (2011) · Gut

Liver physiology and pathologyImmune Cell Function and Interaction

Cited by 127

Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling

Rosenberg, N., Van Haele, M., Lanton, T., Brashi, N., Bromberg, Z., Adler, H., Giladi, H., Peled, A., Goldenberg, D. S., Axelrod, J. H., et al. (2022) · Journal of Hepatology

Liver physiology and pathologyHepatocellular Carcinoma Treatment and Prognosis

Cited by 72

Insulin Signaling as a Potential Natural Killer Cell Checkpoint in Fatty Liver Disease

Amer, J., Salhab, A., Noureddin, M., Doron, S., Abu‐Tair, L., Ghantous, R., Mahamid, M., & Safadi, R. (2018) · Hepatology Communications

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 42

Multiple Roles of IL6 in Hepatic Injury, Steatosis, and Senescence Aggregate to Suppress Tumorigenesis

Shriki, A., Lanton, T., Sonnenblick, A., Levkovitch-Siany, O., Eidelshtein, D., Abramovitch, R., Rosenberg, N., Pappo, O., Elgavish, S., Nevo, Y., et al. (2021) · Cancer Research

Liver physiology and pathologyCytokine Signaling Pathways and Interactions

Cited by 34

Natural Killer Cell-Dependent Anti-Fibrotic Pathway in Liver Injury via Toll-Like Receptor-9

Abu-Tair, L., Axelrod, J. H., Doron, S., Ovadya, Y., Krizhanovsky, V., Galun, E., Amer, J., & Safadi, R. (2013) · PLoS ONE

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 28