Freyer, Christoph

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

Ross, J. M., Stewart, J. B., Hagström, E., Brené, S., Mourier, A., Coppotelli, G., Freyer, C., Lagouge, M., Hoffer, B. J., Olson, L., et al. (2013) · Nature

Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms

Cited by 273

TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication

Milenkovic, D., Matic, S., Kuhl, I., Ruzzenente, B., Freyer, C., Jemt, E., Park, C. B., Falkenberg, M., & Larsson, N.-G. (2013) · Human Molecular Genetics

Mitochondrial Function and PathologyDNA Repair Mechanisms

Cited by 173

Respiratory chain dysfunction in skeletal muscle does not cause insulin resistance

Wredenberg, A., Freyer, C., Sandström, M. E., Katz, A., Wibom, R., Westerblad, H., & Larsson, N.-G. (2006) · Biochemical and Biophysical Research Communications

Metabolism, Diabetes, and CancerMitochondrial Function and Pathology

Cited by 141

Regulation of DNA replication at the end of the mitochondrial D-loop involves the helicase TWINKLE and a conserved sequence element

Jemt, E., Persson, Ö., Shi, Y., Mehmedovic, M., Uhler, J. P., Dávila López, M., Freyer, C., Gustafsson, C. M., Samuelsson, T., & Falkenberg, M. (2015) · Nucleic Acids Research

Mitochondrial Function and PathologyDNA Repair Mechanisms

Cited by 121

Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy

Gineste, C., Hernandez, A., Ivarsson, N., Cheng, A. J., Naess, K., Wibom, R., Lesko, N., Bruhn, H., Wedell, A., Freyer, C., et al. (2015) · Human Molecular Genetics

Mitochondrial Function and PathologyMuscle Physiology and Disorders

Cited by 21

The mitochondrial methylation potential gates mitoribosome assembly

Glasgow, R. I. C., Singh, V., Peña-Pérez, L., Wilhalm, A., Moedas, M. F., Moore, D., Rosenberger, F. A., Li, X., Atanassov, I., Saba, M., et al. (2024) · Nature Communications

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 14

The mitochondrial methylation potential gates mitoribosome assembly

Glasgow, R. I. C., Singh, V., Peña-Pérez, L., Wilhalm, A., Moedas, M. F., Moore, D., Rosenberger, F. A., Li, X., Atanassov, I., Saba, M., et al. (2025) · Nature Communications

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 14