Chicas, Agustin

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

Zuber, J., Shi, J., Wang, E., Rappaport, A. R., Herrmann, H., Sison, E. A., Magoon, D., Qi, J., Blatt, K., Wunderlich, M., et al. (2011) · Nature

Protein Degradation and InhibitorsAcute Myeloid Leukemia Research

Cited by 1,870

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

Chien, Y., Scuoppo, C., Wang, X., Fang, X., Balgley, B., Bolden, J. E., Premsrirut, P., Luo, W., Chicas, A., Lee, C. S., et al. (2011) · Genes & Development

Telomeres, Telomerase, and SenescenceNF-κB Signaling Pathways

Cited by 1,046

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

Freed-Pastor, W. A., Mizuno, H., Zhao, X., Langerød, A., Moon, S.-H., Rodriguez-Barrueco, R., Barsotti, A., Chicas, A., Li, W., Polotskaia, A., et al. (2012) · Cell

Cancer, Lipids, and MetabolismCancer-related Molecular Pathways

Cited by 865

A novel role for high-mobility group A proteins in cellular senescence and heterochromatin formation

Narita, M., Narita, M., Krizhanovsky, V., Nuñez, S., Chicas, A., Hearn, S. A., Myers, M. P., & Lowe, S. W. (2006) · Cell

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 629

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance

Tasdemir, N., Banito, A., Roe, J.-S., Alonso-Curbelo, D., Camiolo, M., Tschaharganeh, D. F., Huang, C.-H., Aksoy, O., Bolden, J. E., Chen, C.-C., et al. (2016) · Cancer Discovery

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 415

Dissecting the Unique Role of the Retinoblastoma Tumor Suppressor during Cellular Senescence

Chicas, A., Wang, X., Zhang, C., McCurrach, M., Zhao, Z., Mert, O., Dickins, R. A., Narita, M., Zhang, M., & Lowe, S. W. (2010) · Cancer Cell

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 388

Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation

Chandra, T., Kirschner, K., Thuret, J.-Y., Pope, B. D., Ryba, T., Newman, S., Ahmed, K., Samarajiwa, S. A., Salama, R., Carroll, T., et al. (2012) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 308