Magno, Lorenza

Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics

Harris, K. D., Hochgerner, H., Skene, N. G., Magno, L., Katona, L., Bengtsson Gonzales, C., Somogyi, P., Kessaris, N., Linnarsson, S., & Hjerling-Leffler, J. (2018) · PLoS Biology

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 276

Alzheimer’s disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph

Magno, L., Lessard, C. B., Martins, M., Lang, V., Cruz, P., Asi, Y., Katan, M., Bilsland, J., Lashley, T., Chakrabarty, P., et al. (2019) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 143

TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation

Magno, L., Bunney, T. D., Mead, E., Svensson, F., & Bictash, M. N. (2021) · Molecular Neurodegeneration

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

Cited by 64

PLCγ2 regulates TREM2 signalling and integrin-mediated adhesion and migration of human iPSC-derived macrophages

Obst, J., Hall-Roberts, H. L., Smith, T. B., Kreuzer, M., Magno, L., Di Daniel, E., Davis, J. B., & Mead, E. (2021) · Scientific Reports

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 36

The hypermorphic PLCγ2 S707Y variant dysregulates microglial cell function – Insight into PLCγ2 activation in brain health and disease, and opportunities for therapeutic modulation

Bull, D., Matte, J. C., Navarron, C. M., McIntyre, R., Whiting, P., Katan, M., Ducotterd, F., & Magno, L. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

Cited by 3