Goodrich, James A.

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

Kaneko, H., Dridi, S., Tarallo, V., Gelfand, B. D., Fowler, B. J., Cho, W. G., Kleinman, M. E., Ponicsan, S. L., Hauswirth, W. W., Chiodo, V. A., et al. (2011) · Nature

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 601

DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88

Tarallo, V., Hirano, Y., Gelfand, B. D., Dridi, S., Kerur, N., Kim, Y., Cho, W. G., Kaneko, H., Fowler, B. J., Bogdanovich, S., et al. (2012) · Cell

Inflammasome and immune disordersRetinal Diseases and Treatments

Cited by 592

Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II

Hofmann, W. A., Stojiljkovic, L., Fuchsova, B., Vargas, G. M., Mavrommatis, E., Philimonenko, V., Kysela, K., Goodrich, J. A., Lessard, J. L., Hope, T. J., et al. (2004) · Nature Cell Biology

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 357

Non-coding-RNA regulators of RNA polymerase II transcription

Goodrich, J. A., & Kugel, J. F. (2006) · Nature Reviews Molecular Cell Biology

Cancer-related molecular mechanisms researchGenomics and Chromatin Dynamics

Cited by 273

Repression of p53-mediated transcription by MDM2: a dual mechanism

Thut, C. J., Goodrich, J. A., & Tjian, R. (1997) · Genes & Development

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 272

ERK1/2 activation is a therapeutic target in age-related macular degeneration

Dridi, S., Hirano, Y., Tarallo, V., Kim, Y., Fowler, B. J., Ambati, B. K., Bogdanovich, S., Chiodo, V. A., Hauswirth, W. W., Kugel, J. F., et al. (2012) · Proceedings of the National Academy of Sciences

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 105