Larsson, Ola

mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation

Morita, M., Gravel, S.-P., Chénard, V., Sikström, K., Zheng, L., Alain, T., Gandin, V., Avizonis, D., Arguello, M., Zakaria, C., et al. (2013) · Cell Metabolism

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

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Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages

Timmons, J. A., Wennmalm, K., Larsson, O., Walden, T. B., Lassmann, T., Petrovic, N., Hamilton, D. L., Gimeno, R. E., Wahlestedt, C., Baar, K., et al. (2007) · Proceedings of the National Academy of Sciences

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

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mTOR coordinates protein synthesis, mitochondrial activity and proliferation

Morita, M., Gravel, S.-P., Hulea, L., Larsson, O., Pollak, M., St-Pierre, J., & Topisirovic, I. (2015) · Cell Cycle

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 552

Leishmania Repression of Host Translation through mTOR Cleavage Is Required for Parasite Survival and Infection

Jaramillo, M., Gomez, M. A., Larsson, O., Shio, M. T., Topisirovic, I., Contreras, I., Luxenburg, R., Rosenfeld, A., Colina, R., McMaster, R. W., et al. (2011) · Cell Host & Microbe

Research on Leishmaniasis StudiesPI3K/AKT/mTOR signaling in cancer

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Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration?

Scheele, C., Nielsen, A. R., Walden, T. B., Sewell, D. A., Fischer, C. P., Brogan, R. J., Petrovic, N., Larsson, O., Tesch, P. A., Wennmalm, K., et al. (2007) · The FASEB Journal

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 110

Generally applicable transcriptome-wide analysis of translational efficiency using anota2seq

Oertlin, C., Lorent, J., Gandin, V., Murie, C., Masvidal, L., Cargnello, M., Furic, L., Topisirovic, I., & Larsson, O. (2017) · Nucleic Acids Research

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 107

Generally applicable transcriptome-wide analysis of translation using anota2seq

Oertlin, C., Lorent, J., Murie, C., Furic, L., Topisirovic, I., & Larsson, O. (2019) · Nucleic Acids Research

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 107

eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

Chan, K., Robert, F., Oertlin, C., Kapeller-Libermann, D., Avizonis, D., Gutierrez, J., Handly-Santana, A., Doubrovin, M., Park, J., Schoepfer, C., et al. (2019) · Nature Communications

Pancreatic and Hepatic Oncology ResearchCancer, Hypoxia, and Metabolism

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Polysome-profiling in small tissue samples

Liang, S., Bellato, H. M., Lorent, J., Lupinacci, F. C. S., Oertlin, C., van Hoef, V., Andrade, V. P., Roffé, M., Masvidal, L., Hajj, G. N. M., et al. (2018) · Nucleic Acids Research

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 78

Polysome-profiling in small tissue samples

Liang, S., Bellato, H., Lorent, J., Lupinacci, F., Van Hoef, V., Masvidal, L., Hajj, G., & Larsson, O. (2017) · Nucleic Acids Research

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 78

Estrogen receptor alpha controls gene expression via translational offsetting

Lorent, J., Rebello, R. J., Hoef, V. V., Lawrence, M. G., Szkop, K. J., Kusnadi, E., Samreen, B., Balanathan, P., Scharmann, K., Takizawa, I., et al. (2018) · The EMBO Journal

Estrogen and related hormone effectsRNA and protein synthesis mechanisms

Cited by 46

Translational offsetting as a mode of estrogen receptor α‐dependent regulation of gene expression

Lorent, J., Kusnadi, E. P., van Hoef, V., Rebello, R. J., Leibovitch, M., Ristau, J., Chen, S., Lawrence, M. G., Szkop, K. J., Samreen, B., et al. (2019) · The EMBO Journal

Estrogen and related hormone effectsRNA and protein synthesis mechanisms

Cited by 46

Translatome-based classification reveals a dual metabolic dependency of a new tumor subtype of pancreatic cancer

Shin, S., Nicolle, R., Jean, C., Samain, R., Ayadi, M., Raffenne, J., Brunel, A., Solorzano, J., Neuzillet, C., Joffre, C., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

Pancreatic and Hepatic Oncology ResearchRNA and protein synthesis mechanisms

Cited by 3

Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics

Papadopoli, D., Palia, R., Jovanovic, P., Tabariès, S., Ciccolini, E., Sabourin, V., Igelmann, S., McLaughlan, S., Zhan, L., Kim, H., et al. (2026) · eLife

Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism

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Decoding the Integrated Stress Response of Pancreatic Cancer: Identifying a Serine‐dependent Tumor Subset Under Metabolic Relationships With CAFs.

Shin, S., Liauzun, M., Solorzano, J., Bras, M. L., Jean, C., Fourneaux, B., Dore, M., Fevrier, L., Belhabib, I., Brunel, A., et al. (2026) · Advanced Science

Pancreatic and Hepatic Oncology ResearchCancer, Hypoxia, and Metabolism

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