Koshiji, Minori

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

Le, D. T., Uram, J. N., Wang, H., Bartlett, B. R., Kemberling, H., Eyring, A. D., Skora, A. D., Luber, B. S., Azad, N. S., Laheru, D., et al. (2015) · New England Journal of Medicine

Cancer Immunotherapy and BiomarkersGenetic factors in colorectal cancer

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HIF-1α induces cell cycle arrest by functionally counteracting Myc

Koshiji, M., Kageyama, Y., Pete, E. A., Horikawa, I., Barrett, J. C., & Huang, L. E. (2004) · The EMBO Journal

Cancer, Hypoxia, and MetabolismCancer-related Molecular Pathways

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HIF-1α Induces Genetic Instability by Transcriptionally Downregulating MutSα Expression

Koshiji, M., To, K. K.-W., Hammer, S., Kumamoto, K., Harris, A. L., Modrich, P., & Huang, L. E. (2005) · Molecular Cell

Cancer, Hypoxia, and MetabolismDNA Repair Mechanisms

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Phase 3, open-label, randomized study of first-line pembrolizumab (pembro) vs. investigator-choice chemotherapy for mismatch repair-deficient (dMMR) or microsatellite instability-high (MSI-H) metastatic colorectal carcinoma (mCRC): KEYNOTE-177

Diaz, L. A., Le, D. T., Yoshino, T., Andre, T., Bendell, J. C., Koshiji, M., Zhang, Y., Kang, S. P., Lam, B., & Jaeger, D. (2017) · Journal of Clinical Oncology

Colorectal Cancer Treatments and StudiesCancer Immunotherapy and Biomarkers

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