Guzy, Robert D.

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

Guzy, R. D., Hoyos, B., Robin, E., Chen, H., Liu, L., Mansfield, K. D., Simon, M. C., Hammerling, U., & Schumacker, P. T. (2005) · Cell Metabolism

Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology

Cited by 1,545

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

Reyfman, P. A., Walter, J. M., Joshi, N., Anekalla, K. R., McQuattie-Pimentel, A. C., Chiu, S., Fernandez, R., Akbarpour, M., Chen, C.-I., Ren, Z., et al. (2019) · American Journal of Respiratory and Critical Care Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisSingle-cell and spatial transcriptomics

Cited by 1,203

Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia

Guzy, R. D., & Schumacker, P. T. (2006) · Experimental Physiology

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 881

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-α activation

Mansfield, K. D., Guzy, R. D., Pan, Y., Young, R. M., Cash, T. P., Schumacker, P. T., & Simon, M. C. (2005) · Cell Metabolism

Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress

Cited by 606

Loss of the SdhB, but Not the SdhA, Subunit of Complex II Triggers Reactive Oxygen Species-Dependent Hypoxia-Inducible Factor Activation and Tumorigenesis

Guzy, R. D., Sharma, B., Bell, E., Chandel, N. S., & Schumacker, P. T. (2008) · Molecular and Cellular Biology

Cancer, Hypoxia, and MetabolismCancer and biochemical research

Cited by 427

Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells

Waypa, G. B., Guzy, R., Mungai, P. T., Mack, M. M., Marks, J. D., Roe, M. W., & Schumacker, P. T. (2006) · Circulation Research

Pulmonary Hypertension Research and TreatmentsRedox biology and oxidative stress

Cited by 191