Hayer, Silvia

Osteoclasts are essential for TNF-α-mediated joint destruction.

Redlich, K., Hayer, S., Ricci, R., David, J.-P., Tohidast-Akrad, M., Kollias, G., Steiner, G., Smolen, J. S., Wagner, E. F., & Schett, G. (2002) · Journal of Clinical Investigation

Rheumatoid Arthritis Research and TherapiesBone Metabolism and Diseases

Cited by 474

Tumor necrosis factor α-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin.

Redlich, K., Hayer, S., Maier, A., Dunstan, C. R., Tohidast‐Akrad, M., Lang, S., Türk, B., Pietschmann, P., Woloszczuk, W., Haralambous, S., et al. (2002) · Arthritis & Rheumatism

Rheumatoid Arthritis Research and TherapiesBone Metabolism and Diseases

Cited by 285

Myostatin is a direct regulator of osteoclast differentiation and its inhibition reduces inflammatory joint destruction in mice

Dankbar, B., Fennen, M., Brunert, D., Hayer, S., Frank, S., Wehmeyer, C., Beckmann, D., Paruzel, P., Bertrand, J., Redlich, K., et al. (2015) · Nature Medicine

Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies

Cited by 262

Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice.

Schett, G., Redlich, K., Hayer, S., Zwerina, J., Bolon, B., Dunstan, C., Görtz, B., Schulz, A., Bergmeister, H., Kollias, G., et al. (2003) · Arthritis & Rheumatism

Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies

Cited by 150

Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis.

Redlich, K., Görtz, B., Hayer, S., Zwerina, J., Doerr, N., Kostenuik, P., Bergmeister, H., Kollias, G., Steiner, G., Smolen, J. S., et al. (2004) · The American Journal of Pathology

Rheumatoid Arthritis Research and TherapiesBone Metabolism and Diseases

Cited by 134

Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis.

Herrak, P., Görtz, B., Hayer, S., Redlich, K., Reiter, E., Gasser, J., Bergmeister, H., Kollias, G., Smolen, J. S., & Schett, G. (2004) · Arthritis & Rheumatism

Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies

Cited by 110