Klaassen, Curtis D.

Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

Kong, B., Wang, L., Chiang, J. Y. L., Zhang, Y., Klaassen, C. D., & Guo, G. L. (2012) · Hepatology

Drug Transport and Resistance MechanismsCholesterol and Lipid Metabolism

Cited by 456

Beneficial role of Nrf2 in regulating NADPH generation and consumption

Wu, K. C., Cui, J. Y., & Klaassen, C. D. (2011) · Toxicological Sciences

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 368

Regulation of hepatic drug-metabolizing enzymes in germ-free mice by conventionalization and probiotics

Selwyn, F. P., Cheng, S. L., Klaassen, C. D., & Cui, J. Y. (2016) · Drug Metabolism and Disposition

Pharmacogenetics and Drug MetabolismGut microbiota and health

Cited by 138

Repeated administration of berberine inhibits cytochromes P450 in humans

Guo, Y., Chen, Y., Tan, Z.-R., Klaassen, C. D., & Zhou, H.-H. (2012) · European Journal of Clinical Pharmacology

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 137

RNA-Seq Quantification of Hepatic Drug Processing Genes in Germ-Free Mice

Selwyn, F. P., Cui, J. Y., & Klaassen, C. D. (2015) · Drug Metabolism and Disposition

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 122

Importance of Hepatic Induction of Constitutive Androstane Receptor and Other Transcription Factors That Regulate Xenobiotic Metabolism and Transport

Petrick, J. S., & Klaassen, C. D. (2007) · Drug Metabolism and Disposition

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 85

Dose-response of berberine on hepatic cytochromes P450 mRNA expression and activities in mice

Guo, Y., Pope, C., Cheng, X., Zhou, H., & Klaassen, C. D. (2011) · Journal of Ethnopharmacology

Pharmacogenetics and Drug MetabolismBerberine and alkaloids research

Cited by 77

Constitutive Androstane Receptor-Mediated Changes in Bile Acid Composition Contributes to Hepatoprotection from Lithocholic Acid-Induced Liver Injury in Mice

Beilke, L. D., Aleksunes, L. M., Holland, R. D., Besselsen, D. G., Beger, R. D., Klaassen, C. D., & Cherrington, N. J. (2009) · Drug Metabolism and Disposition

Drug Transport and Resistance MechanismsDrug-Induced Hepatotoxicity and Protection

Cited by 73

Coordinated induction of Nrf2 target genes protects against iron nitrilotriacetate (FeNTA)-induced nephrotoxicity

TANAKA, Y., ALEKSUNES, L., GOEDKEN, M., CHEN, C., REISMAN, S., MANAUTOU, J., & KLAASSEN, C. (2008) · Toxicology and Applied Pharmacology

Genomics, phytochemicals, and oxidative stressAcute Kidney Injury Research

Cited by 60

Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmetics

Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., Marks, J. G., Shank, R. C., Slaga, T. J., Snyder, P. W., et al. (2018) · International Journal of Toxicology

Contact Dermatitis and AllergiesSkin Protection and Aging

Cited by 41

Activation of Constitutive Androstane Receptor (CAR) in mice results in maintained biliary excretion of bile acids despite a marked decrease of bile acids in liver

Lickteig, A. J., Csanaky, I. L., Pratt-Hyatt, M., & Klaassen, C. D. (2016) · Toxicological Sciences

Drug Transport and Resistance MechanismsCholesterol and Lipid Metabolism

Cited by 26

Final Report of the Amended Safety Assessment of PVM/MA Copolymer and Its Related Salts and Esters as Used in Cosmetics

Burnett, C. L., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., Marks, J. G., Shank, R. C., Slaga, T. J., Snyder, P. W., et al. (2011) · International Journal of Toxicology

Contact Dermatitis and AllergiesCarcinogens and Genotoxicity Assessment

Cited by 25

Safety assessment of polyglyceryl fatty acid esters as used in cosmetics

Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., Marks, J. G., Shank, R. C., Slaga, T. J., Snyder, P. W., et al. (2023) · International Journal of Toxicology

Contact Dermatitis and AllergiesSurfactants and Colloidal Systems

Cited by 16

Amended safety assessment of methylchloroisothiazolinone and methylisothiazolinone as used in cosmetics

Burnett, C. L., Bergfeld, W. F., Belsito, D. V., Klaassen, C. D., Liebler, D. C., Marks, J. G., Peterson, L. A., Shank, R. C., Slaga, T. J., Snyder, P. W., et al. (2021) · International Journal of Toxicology

Contact Dermatitis and AllergiesAntimicrobial agents and applications

Cited by 12

Effects of absence of Constitutive Androstane Receptor (CAR) on bile acid homeostasis in male and female mice

Lickteig, A. J., Zhang, Y., Klaassen, C. D., & Csanaky, I. L. (2019) · Toxicological Sciences

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 7

Safety Assessment of Carbonate Salts as Used in Cosmetics

Johnson, W., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., Marks, J. G., Shank, R. C., Slaga, T. J., Snyder, P. W., et al. (2022) · International Journal of Toxicology

Contact Dermatitis and AllergiesDye analysis and toxicity

Cited by 3