Ludwig, Leif S.

Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells

Mimitou, E. P., Lareau, C. A., Chen, K. Y., Zorzetto-Fernandes, A. L., Hao, Y., Takeshima, Y., Luo, W., Huang, T.-S., Yeung, B. Z., Papalexi, E., et al. (2021) · Nature Biotechnology

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 529

Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

Khajuria, R. K., Munschauer, M., Ulirsch, J. C., Fiorini, C., Ludwig, L. S., McFarland, S. K., Abdulhay, N. J., Specht, H., Keshishian, H., Mani, D. R., et al. (2018) · Cell

RNA and protein synthesis mechanismsHematopoietic Stem Cell Transplantation

Cited by 416

Altered translation of GATA1 in Diamond-Blackfan anemia

Ludwig, L. S., Gazda, H. T., Eng, J. C., Eichhorn, S. W., Thiru, P., Ghazvinian, R., George, T. I., Gotlib, J. R., Beggs, A. H., Sieff, C. A., et al. (2014) · Nature Medicine

Blood disorders and treatmentsRNA and protein synthesis mechanisms

Cited by 302

The Genetic Landscape of Diamond-Blackfan Anemia

Ulirsch, J. C., Verboon, J. M., Kazerounian, S., Guo, M. H., Yuan, D., Ludwig, L. S., Handsaker, R. E., Abdulhay, N. J., Fiorini, C., Genovese, G., et al. (2018) · The American Journal of Human Genetics

Blood disorders and treatmentsGenomics and Rare Diseases

Cited by 272

Interrogation of human hematopoiesis at single-cell and single-variant resolution

Ulirsch, J. C., Lareau, C. A., Bao, E. L., Ludwig, L. S., Guo, M. H., Benner, C., Satpathy, A. T., Kartha, V. K., Salem, R. M., Hirschhorn, J. N., et al. (2019) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 208

Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC

Fiskin, E., Lareau, C. A., Ludwig, L. S., Eraslan, G., Liu, F., Ring, A. M., Xavier, R. J., & Regev, A. (2022) · Nature Biotechnology

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 68

Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking

Lareau, C. A., Ludwig, L. S., & Sankaran, V. G. (2019) · Blood Advances

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 17