Osborne, Timothy F.

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

Freed-Pastor, W. A., Mizuno, H., Zhao, X., Langerød, A., Moon, S.-H., Rodriguez-Barrueco, R., Barsotti, A., Chicas, A., Li, W., Polotskaia, A., et al. (2012) · Cell

Cancer, Lipids, and MetabolismCancer-related Molecular Pathways

Cited by 865

Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity

Kidani, Y., Elsaesser, H., Hock, M. B., Vergnes, L., Williams, K. J., Argus, J. P., Marbois, B. N., Komisopoulou, E., Wilson, E. B., Osborne, T. F., et al. (2013) · Nature Immunology

T-cell and B-cell ImmunologyCancer, Lipids, and Metabolism

Cited by 552

Sterol Regulatory Element-binding Proteins (SREBPs): Key Regulators of Nutritional Homeostasis and Insulin Action

Osborne, T. F. (2000) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 521

A feed-forward loop amplifies nutritional regulation of PNPLA3

Huang, Y., He, S., Li, J. Z., Seo, Y.-K., Osborne, T. F., Cohen, J. C., & Hobbs, H. H. (2010) · Proceedings of the National Academy of Sciences

Liver Disease Diagnosis and TreatmentLipid metabolism and biosynthesis

Cited by 386

Partitioning Circadian Transcription by SIRT6 Leads to Segregated Control of Cellular Metabolism

Masri, S., Rigor, P., Cervantes, M., Ceglia, N., Sebastian, C., Xiao, C., Roqueta-Rivera, M., Deng, C., Osborne, T. F., Mostoslavsky, R., et al. (2014) · Cell

Circadian rhythm and melatoninSirtuins and Resveratrol in Medicine

Cited by 292

Gut bitter taste receptor signalling induces ABCB1 through a mechanism involving CCK

Jeon, T.-I., Seo, Y.-K., & Osborne, T. F. (2011) · Biochemical Journal

Biochemical Analysis and Sensing TechniquesDrug Transport and Resistance Mechanisms

Cited by 127

Promoter selective transcriptional synergy mediated by sterol regulatory element binding protein and Sp1: a critical role for the Btd domain of sp1

Athanikar, J. N., Sanchez, H. B., & Osborne, T. F. (1997) · Molecular and Cellular Biology

Cancer, Lipids, and MetabolismCholesterol and Lipid Metabolism

Cited by 88