Crooke, Stanley T.

RNA-Targeted Therapeutics

Crooke, S. T., Witztum, J. L., Bennett, C. F., & Baker, B. F. (2018) · Cell Metabolism

RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry

Cited by 841

Antisense technology: an overview and prospectus

Crooke, S. T., Baker, B. F., Crooke, R. M., & Liang, X.-H. (2021) · Nature Reviews Drug Discovery

RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry

Cited by 775

Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials

Viney, N. J., van Capelleveen, J. C., Geary, R. S., Xia, S., Tami, J. A., Yu, R. Z., Marcovina, S. M., Hughes, S. G., Graham, M. J., Crooke, R. M., et al. (2016) · The Lancet

Lipoproteins and Cardiovascular HealthLipid metabolism and disorders

Cited by 754

Cellular uptake and trafficking of antisense oligonucleotides

Crooke, S. T., Wang, S., Vickers, T. A., Shen, W., & Liang, X.-H. (2017) · Nature Biotechnology

RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry

Cited by 582

Efficient Reduction of Target RNAs by Small Interfering RNA and RNase H-dependent Antisense Agents

Vickers, T. A., Koo, S., Bennett, C. F., Crooke, S. T., Dean, N. M., & Baker, B. F. (2003) · Journal of Biological Chemistry

RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry

Cited by 461

Progress in antisense technology

Crooke, S. T. (2004) · Annual Review of Medicine

RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry

Cited by 417

Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans

Graham, M. J., Lee, R. G., Bell, T. A., Fu, W., Mullick, A. E., Alexander, V. J., Singleton, W., Viney, N., Geary, R., Su, J., et al. (2013) · Circulation Research

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 377

Phosphorothioate modified oligonucleotide–protein interactions

Crooke, S. T., Vickers, T. A., & Liang, X.-H. (2020) · Nucleic Acids Research

RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry

Cited by 372

The Effects of 2′- O -Methoxyethyl Containing Antisense Oligonucleotides on Platelets in Human Clinical Trials

Crooke, S. T., Baker, B. F., Witztum, J. L., Kwoh, T. J., Pham, N. C., Salgado, N., McEvoy, B. W., Cheng, W., Hughes, S. G., Bhanot, S., et al. (2017) · Nucleic Acid Therapeutics

RNA Interference and Gene DeliveryPlatelet Disorders and Treatments

Cited by 129

Integrated Assessment of the Clinical Performance of GalNAc 3 -Conjugated 2′- O -Methoxyethyl Chimeric Antisense Oligonucleotides: I. Human Volunteer Experience

Crooke, S. T., Baker, B. F., Xia, S., Yu, R. Z., Viney, N. J., Wang, Y., Tsimikas, S., & Geary, R. S. (2019) · Nucleic Acid Therapeutics

RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry

Cited by 127

Glucocorticoid regulation of beta-adrenergic receptors in 3T3-L1 preadipocytes.

Nakada, M. T., Stadel, J. M., Poksay, K. S., & Crooke, S. T. (1987) · Molecular Pharmacology

Receptor Mechanisms and SignalingEstrogen and related hormone effects

Cited by 78