Vocadlo, David J.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

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A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

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Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation

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The Emerging Link between O-GlcNAc and Alzheimer Disease

Zhu, Y., Shan, X., Yuzwa, S. A., & Vocadlo, D. J. (2014) · Journal of Biological Chemistry

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Drosophila O -GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs ( sxc )

Sinclair, D. A. R., Syrzycka, M., Macauley, M. S., Rastgardani, T., Komljenovic, I., Vocadlo, D. J., Brock, H. W., & Honda, B. M. (2009) · Proceedings of the National Academy of Sciences

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Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice

Hastings, N. B., Wang, X., Song, L., Butts, B. D., Grotz, D., Hargreaves, R., Fred Hess, J., Hong, K.-L. K., Huang, C. R.-R., Hyde, L., et al. (2017) · Molecular Neurodegeneration

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O-GlcNAc occurs cotranslationally to stabilize nascent polypeptide chains

Zhu, Y., Liu, T.-W., Cecioni, S., Eskandari, R., Zandberg, W. F., & Vocadlo, D. J. (2015) · Nature Chemical Biology

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Mapping O-GlcNAc modification sites on tau and generation of a site-specific O-GlcNAc tau antibody

Yuzwa, S. A., Yadav, A. K., Skorobogatko, Y., Clark, T., Vosseller, K., & Vocadlo, D. J. (2011) · Amino Acids

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