Michels, Birgitta E.

3D model for CAR‐mediated cytotoxicity using patient‐derived colorectal cancer organoids

Schnalzger, T. E., de Groot, M. H., Zhang, C., Mosa, M. H., Michels, B. E., Röder, J., Darvishi, T., Wels, W. S., & Farin, H. F. (2019) · The EMBO Journal

CAR-T cell therapy researchImmune Cell Function and Interaction

Cited by 354

Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids

Michels, B. E., Mosa, M. H., Streibl, B. I., Zhan, T., Menche, C., Abou-El-Ardat, K., Darvishi, T., Członka, E., Wagner, S., Winter, J., et al. (2020) · Cell Stem Cell

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 222

Colorectal cancer organoid-stroma biobank allows subtype-specific assessment of individualized therapy responses

Farin, H. F., Mosa, M. H., Ndreshkjana, B., Grebbin, B. M., Ritter, B., Menche, C., Kennel, K. B., Ziegler, P. K., Szabó, L., Bollrath, J., et al. (2023) · Cancer Discovery

Cancer Cells and MetastasisColorectal Cancer Treatments and Studies

Cited by 120

Intestinal brush border formation requires a TMIGD1-based intermicrovillar adhesion complex

Hartmann, C., Thüring, E.-M., Greune, L., Michels, B. E., Pajonczyk, D., Leußink, S., Brinkmann, F., Glaesner-Ebnet, M., Wardelmann, E., Zobel, T., et al. (2022) · Science Signaling

Cell Adhesion Molecules ResearchSkin and Cellular Biology Research

Cited by 19

Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1

Thüring, E.-M., Hartmann, C., Maddumage, J. C., Javorsky, A., Michels, B. E., Gerke, V., Banks, L., Humbert, P. O., Kvansakul, M., & Ebnet, K. (2023) · Communications Biology

Cell Adhesion Molecules ResearchHippo pathway signaling and YAP/TAZ

Cited by 7