Keith, Curtis T.

A mammalian protein targeted by G1-arresting rapamycin–receptor complex

Brown, E. J., Albers, M. W., Bum Shin, T., ichikawa, K., Keith, C. T., Lane, W. S., & Schreiber, S. L. (1994) · Nature

PI3K/AKT/mTOR signaling in cancerSignaling Pathways in Disease

Cited by 2,053

Multi-target therapeutics: when the whole is greater than the sum of the parts

Zimmermann, G. R., Lehár, J., & Keith, C. T. (2007) · Drug Discovery Today

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 1,105

Multicomponent therapeutics for networked systems

Keith, C. T., Borisy, A. A., & Stockwell, B. R. (2005) · Nature Reviews Drug Discovery

Computational Drug Discovery MethodsGene Regulatory Network Analysis

Cited by 769

Systematic discovery of multicomponent therapeutics

Borisy, A. A., Elliott, P. J., Hurst, N. W., Lee, M. S., Lehár, J., Price, E. R., Serbedzija, G., Zimmermann, G. R., Foley, M. A., Stockwell, B. R., et al. (2003) · Proceedings of the National Academy of Sciences

Computational Drug Discovery MethodsHistorical Medical Research and Treatments

Cited by 620

Chemical combination effects predict connectivity in biological systems

Lehár, J., Zimmermann, G. R., Krueger, A. S., Molnar, R. A., Ledell, J. T., Heilbut, A. M., Short, G. F., Giusti, L. C., Nolan, G. P., Magid, O. A., et al. (2007) · Molecular Systems Biology

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

Cited by 275

cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein.

Cimprich, K. A., Shin, T. B., Keith, C. T., & Schreiber, S. L. (1996) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsPI3K/AKT/mTOR signaling in cancer

Cited by 273