Burkhardt, Daniel B.

Visualizing structure and transitions in high-dimensional biological data

Moon, K. R., van Dijk, D., Wang, Z., Gigante, S., Burkhardt, D. B., Chen, W. S., Yim, K., Elzen, A. V. D., Hirn, M. J., Coifman, R. R., et al. (2019) · Nature Biotechnology

Single-cell and spatial transcriptomicsTopological and Geometric Data Analysis

Cited by 1,065

Quantifying the effect of experimental perturbations at single-cell resolution

Burkhardt, D. B., Stanley, J. S., Tong, A., Perdigoto, A. L., Gigante, S. A., Herold, K. C., Wolf, G., Giraldez, A. J., van Dijk, D., & Krishnaswamy, S. (2021) · Nature Biotechnology

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 226

Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma

Chung, K. M., Singh, J., Lawres, L., Dorans, K. J., Garcia, C., Burkhardt, D. B., Robbins, R., Bhutkar, A., Cardone, R., Zhao, X., et al. (2020) · Cell

Pancreatic and Hepatic Oncology ResearchCancer, Lipids, and Metabolism

Cited by 150

Multimodal single cell data integration challenge: results and lessons learned

Lance, C., Luecken, M. D., Burkhardt, D. B., Cannoodt, R., Rautenstrauch, P., Laddach, A., Ubingazhibov, A., Cao, Z.-J., Deng, K., Khan, S., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 81

Multiscale PHATE identifies multimodal signatures of COVID-19

Kuchroo, M., Huang, J., Wong, P., Grenier, J.-C., Shung, D., Tong, A., Lucas, C., Klein, J., Burkhardt, D. B., Gigante, S., et al. (2022) · Nature Biotechnology

Single-cell and spatial transcriptomicsTopological and Geometric Data Analysis

Cited by 72

MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors

Chen, X., Burkhardt, D. B., Hartman, A. A., Hu, X., Eastman, A. E., Sun, C., Wang, X., Zhong, M., Krishnaswamy, S., & Guo, S. (2019) · Nature Communications

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 58