Arumugam, Thiruma V.

Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States

Mattson, M. P., & Arumugam, T. V. (2018) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 1,242

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

Gelderblom, M., Leypoldt, F., Steinbach, K., Behrens, D., Choe, C.-U., Siler, D. A., Arumugam, T. V., Orthey, E., Gerloff, C., Tolosa, E., et al. (2009) · Stroke

Neuroinflammation and Neurodegeneration MechanismsAcute Ischemic Stroke Management

Cited by 1,066

Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

Tang, S.-C., Arumugam, T. V., Xu, X., Cheng, A., Mughal, M. R., Jo, D. G., Lathia, J. D., Siler, D. A., Chigurupati, S., Ouyang, X., et al. (2007) · Proceedings of the National Academy of Sciences

Neuroinflammation and Neurodegeneration MechanismsImmune Response and Inflammation

Cited by 779

Role of T Lymphocytes and Interferon-γ in Ischemic Stroke

Yilmaz, G., Arumugam, T. V., Stokes, K. Y., & Granger, D. N. (2006) · Circulation

Neuroinflammation and Neurodegeneration MechanismsAcute Ischemic Stroke Management

Cited by 722

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

Gelderblom, M., Weymar, A., Bernreuther, C., Velden, J., Arunachalam, P., Steinbach, K., Orthey, E., Arumugam, T. V., Leypoldt, F., Simova, O., et al. (2012) · Blood

Neuroinflammation and Neurodegeneration MechanismsAcute Ischemic Stroke Management

Cited by 457

HDAC inhibitor sodium butyrate-mediated epigenetic regulation enhances neuroprotective function of microglia during ischemic stroke

Patnala, R., Arumugam, T. V., Gupta, N., & Dheen, S. T. (2017) · Molecular Neurobiology

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 278

Inhibition of Drp1 ameliorates synaptic depression, Aβ deposition, and cognitive impairment in an Alzheimer’s disease model

Baek, S. H., Park, S. J., Jeong, J. I., Kim, S. H., Han, J., Kyung, J. W., Baik, S.-H., Choi, Y., Choi, B. Y., Park, J. S., et al. (2017) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 258

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal

Tang, S.-C., Lathia, J. D., Selvaraj, P. K., Jo, D.-G., Mughal, M. R., Cheng, A., Siler, D. A., Markesbery, W. R., Arumugam, T. V., & Mattson, M. P. (2008) · Experimental Neurology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 232

NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models

Bahn, G., Park, J.-S., Yun, U. J., Lee, Y. J., Choi, Y., Park, J. S., Baek, S. H., Choi, B. Y., Cho, Y. S., Kim, H. K., et al. (2019) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsGenomics, phytochemicals, and oxidative stress

Cited by 210

O -GlcNAcylation ameliorates the pathological manifestations of Alzheimer’s disease by inhibiting necroptosis

Park, J., Ha, H.-J., Chung, E. S., Baek, S. H., Cho, Y., Kim, H. K., Han, J., Sul, J. H., Lee, J., Kim, E., et al. (2021) · Science Advances

Glycosylation and Glycoproteins ResearchAlzheimer's disease research and treatments

Cited by 139

Aging-associated sensory decline and Alzheimer’s disease

Hong, S., Baek, S.-H., Lai, M. K. P., Arumugam, T. V., & Jo, D.-G. (2024) · Molecular Neurodegeneration

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 76

Pancortin-2 Interacts with WAVE1 and Bcl-xL in a Mitochondria-Associated Protein Complex That Mediates Ischemic Neuronal Death

Cheng, A., Arumugam, T. V., Liu, D., Khatri, R. G., Mustafa, K., Kwak, S., Ling, H.-P., Gonzales, C., Xin, O., Jo, D.-G., et al. (2007) · The Journal of Neuroscience

Cell death mechanisms and regulationCardiac Ischemia and Reperfusion

Cited by 56

Predictive Nephrotoxicity Profiling of a Novel Antifungal Small Molecule in Comparison to Amphotericin B and Voriconazole

Udawatte, N. S., Kang, S. W., Wang, Y., Arumugam, T. V., & Seneviratne, C. J. (2020) · Frontiers in Pharmacology

Antifungal resistance and susceptibilityAcute Kidney Injury Research

Cited by 17