Macdonald, Christian B

Molecular basis of proton-sensing by G protein-coupled receptors

Howard, M. K., Hoppe, N., Huang, X.-P., Macdonald, C. B., Mehrota, E., Rockefeller Grimes, P., Zahm, A., Trinidad, D. D., English, J., Coyote-Maestas, W., et al. (2024) · Cell

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 78

Molecular basis of proton sensing by G protein-coupled receptors

Howard, M. K., Hoppe, N., Huang, X.-P., Mitrovic, D., Billesbølle, C. B., Macdonald, C. B., Mehrotra, E., Rockefeller Grimes, P., Trinidad, D. D., Delemotte, L., et al. (2025) · Cell

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 77

Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain

Estevam, G. O., Linossi, E. M., Macdonald, C. B., Espinoza, C. A., Michaud, J. M., Coyote-Maestas, W., Collisson, E. A., Jura, N., & Fraser, J. S. (2024) · eLife

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

Cited by 22

Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning

Estevam, G. O., Linossi, E., Rao, J., Macdonald, C. B., Ravikumar, A., Chrispens, K. M., Capra, J. A., Coyote-Maestas, W., Pimentel, H., Collisson, E. A., et al. (2025) · eLife

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

Cited by 17

Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning

Estevam, G. O., Linossi, E., Rao, J., Macdonald, C. B., Ravikumar, A., Chrispens, K. M., Capra, J. A., Coyote-Maestas, W., Pimentel, H., Collisson, E. A., et al. (2025) · eLife

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

Cited by 6