Cong, Le

Multiplex Genome Engineering Using CRISPR/Cas Systems

Cong, L., Ran, F. A., Cox, D., Lin, S., Barretto, R., Habib, N., Hsu, P. D., Wu, X., Jiang, W., Marraffini, L. A., et al. (2013) · Science

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 15,339

In vivo genome editing using Staphylococcus aureus Cas9

Ran, F. A., Cong, L., Yan, W. X., Scott, D. A., Gootenberg, J. S., Kriz, A. J., Zetsche, B., Shalem, O., Wu, X., Makarova, K. S., et al. (2015) · Nature

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 2,687

MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens

Li, W., Xu, H., Xiao, T., Cong, L., Love, M. I., Zhang, F., Irizarry, R. A., Liu, J. S., Brown, M., & Liu, X. S. (2014) · Genome Biology

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 2,684

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

Tabebordbar, M., Zhu, K., Cheng, J. K. W., Chew, W. L., Widrick, J. J., Yan, W. X., Maesner, C., Wu, E. Y., Xiao, R., Ran, F. A., et al. (2016) · Science

CRISPR and Genetic EngineeringMuscle Physiology and Disorders

Cited by 1,046

Optical control of mammalian endogenous transcription and epigenetic states

Konermann, S., Brigham, M. D., Trevino, A. E., Hsu, P. D., Heidenreich, M., Cong, L., Platt, R. J., Scott, D. A., Church, G. M., & Zhang, F. (2013) · Nature

Photoreceptor and optogenetics researchCRISPR and Genetic Engineering

Cited by 803

Sequence determinants of improved CRISPR sgRNA design

Xu, H., Xiao, T., Chen, C.-H., Li, W., Meyer, C. A., Wu, Q., Wu, D., Cong, L., Zhang, F., Liu, J. S., et al. (2015) · Genome Research

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 625

Adeno-associated viral vector-mediated immune responses: Understanding barriers to gene delivery

Nidetz, N. F., McGee, M. C., Tse, L. V., Li, C., Cong, L., Li, Y., & Huang, W. (2020) · Pharmacology & Therapeutics

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 174

Biomni: A general-purpose biomedical ai agent

Huang, K., Zhang, S., Wang, H., Qu, Y., Lu, Y., Roohani, Y., Li, R., Qiu, L., Li, G., Zhang, J., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory)

Biomedical Text Mining and OntologiesArtificial Intelligence in Healthcare and Education

Cited by 125

Efficient Generation of Transcriptomic Profiles by Random Composite Measurements

Cleary, B., Cong, L., Cheung, A., Lander, E. S., & Regev, A. (2017) · Cell

Gene expression and cancer classificationSparse and Compressive Sensing Techniques

Cited by 114

APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer’s disease pathology

Chemparathy, A., Le Guen, Y., Chen, S., Lee, E.-G., Leong, L., Gorzynski, J. E., Jensen, T. D., Ferrasse, A., Xu, G., Xiang, H., et al. (2024) · Neuron

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 43

Evaluating Large Language Models in Scientific Discovery

Song, Z., Lu, J., Du, Y., Yu, B., Pruyn, T. M., Huang, Y., Guo, K., Luo, X., Qu, Y., Qu, Y., et al. (2025) · arXiv

Topic ModelingArtificial Intelligence Applications

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