Kearney, Conor J.

Tumor immune evasion arises through loss of TNF sensitivity

Kearney, C. J., Vervoort, S. J., Hogg, S. J., Ramsbottom, K. M., Freeman, A. J., Lalaoui, N., Pijpers, L., Michie, J., Brown, K. K., Knight, D. A., et al. (2018) · Science Immunology

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 381

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

Hogg, S. J., Motorna, O., Cluse, L. A., Johanson, T. M., Coughlan, H. D., Raviram, R., Myers, R. M., Costacurta, M., Todorovski, I., Pijpers, L., et al. (2021) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 170

Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction

Fujihara, K. M., Zhang, B. Z., Jackson, T. D., Ogunkola, M. O., Nijagal, B., Milne, J. V., Sallman, D. A., Ang, C.-S., Nikolic, I., Kearney, C. J., et al. (2022) · Science Advances

Ferroptosis and cancer prognosisSulfur Compounds in Biology

Cited by 102

SUGAR-seq enables simultaneous detection of glycans, epitopes, and the transcriptome in single cells

Kearney, C. J., Vervoort, S. J., Ramsbottom, K. M., Todorovski, I., Lelliott, E. J., Zethoven, M., Pijpers, L., Martin, B. P., Semple, T., Martelotto, L., et al. (2021) · Science Advances

Single-cell and spatial transcriptomicsGlycosylation and Glycoproteins Research

Cited by 87

PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF

Kearney, C. J., Lalaoui, N., Freeman, A. J., Ramsbottom, K. M., Silke, J., & Oliaro, J. (2017) · Cell Death & Differentiation

Cell death mechanisms and regulationCancer Immunotherapy and Biomarkers

Cited by 83

DOCK8 regulates signal transduction events to control immunity

Kearney, C. J., Randall, K. L., & Oliaro, J. (2017) · Cellular & Molecular Immunology

Immunodeficiency and Autoimmune DisordersT-cell and B-cell Immunology

Cited by 70

DOCK8 Drives Src-Dependent NK Cell Effector Function

Kearney, C. J., Vervoort, S. J., Ramsbottom, K. M., Freeman, A. J., Michie, J., Peake, J., Casanova, J.-L., Picard, C., Tangye, S. G., Ma, C. S., et al. (2017) · The Journal of Immunology

Immune Cell Function and InteractionImmunodeficiency and Autoimmune Disorders

Cited by 23