Dettmer, Katja

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells

Brand, A., Singer, K., Koehl, G. E., Kolitzus, M., Schoenhammer, G., Thiel, A., Matos, C., Bruss, C., Klobuch, S., Peter, K., et al. (2016) · Cell Metabolism

Cancer, Hypoxia, and MetabolismCancer Immunotherapy and Biomarkers

Cited by 2,039

Srebp-controlled glucose metabolism is essential for NK cell functional responses

Assmann, N., O'Brien, K. L., Donnelly, R. P., Dyck, L., Zaiatz-Bittencourt, V., Loftus, R. M., Heinrich, P., Oefner, P. J., Lynch, L., Gardiner, C. M., et al. (2017) · Nature Immunology

Immune Cell Function and InteractionImmune cells in cancer

Cited by 375

Microbiota Disruption Induced by Early Use of Broad-Spectrum Antibiotics Is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation

Weber, D., Jenq, R. R., Peled, J. U., Taur, Y., Hiergeist, A., Koestler, J., Dettmer, K., Weber, M., Wolff, D., Hahn, J., et al. (2017) · Biology of Blood and Marrow Transplantation

Gut microbiota and healthHematopoietic Stem Cell Transplantation

Cited by 245

A metabolome-wide association study of kidney function and disease in the general population

Sekula, P., Goek, O.-N., Quaye, L., Barrios, C., Levey, A. S., Römisch-Margl, W., Menni, C., Yet, I., Gieger, C., Inker, L. A., et al. (2016) · Journal of the American Society of Nephrology

Metabolomics and Mass Spectrometry StudiesChronic Kidney Disease and Diabetes

Cited by 203

Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome

Weber, D., Oefner, P. J., Hiergeist, A., Koestler, J., Gessner, A., Weber, M., Hahn, J., Wolff, D., Stämmler, F., Spang, R., et al. (2015) · Blood

Gut microbiota and healthHematopoietic Stem Cell Transplantation

Cited by 195

D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization

Böttcher, M., Renner, K., Berger, R., Mentz, K., Thomas, S., Cardenas-Conejo, Z. E., Dettmer, K., Oefner, P. J., Mackensen, A., Kreutz, M., et al. (2018) · OncoImmunology

Cancer, Hypoxia, and MetabolismAcute Myeloid Leukemia Research

Cited by 124

Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen

Siegert, I., Schödel, J., Nairz, M., Schatz, V., Dettmer, K., Dick, C., Kalucka, J., Franke, K., Ehrenschwender, M., Schley, G., et al. (2015) · Cell Reports

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 110

Detrimental effect of broad-spectrum antibiotics on intestinal microbiome diversity in patients after allogeneic stem cell transplantation: lack of commensal sparing antibiotics.

Weber, D., Hiergeist, A., Weber, M., Dettmer, K., Wolff, D., Hahn, J., Herr, W., Gessner, A., & Holler, E. (2019) · Clinical Infectious Diseases

Gut microbiota and healthHematopoietic Stem Cell Transplantation

Cited by 92