Gaudreault, Nathalie

A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis

Thériault, S., Gaudreault, N., Lamontagne, M., Rosa, M., Boulanger, M.-C., Messika-Zeitoun, D., Clavel, M.-A., Capoulade, R., Dagenais, F., Pibarot, P., et al. (2018) · Nature Communications

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 135

ATP acts as a survival signal and prevents the mineralization of aortic valve

Côté, N., El Husseini, D., Pépin, A., Guauque-Olarte, S., Ducharme, V., Bouchard-Cannon, P., Audet, A., Fournier, D., Gaudreault, N., Derbali, H., et al. (2012) · Journal of Molecular and Cellular Cardiology

Adenosine and Purinergic SignalingCardiac Valve Diseases and Treatments

Cited by 95

Genetic Association Analyses Highlight IL6 , ALPL , and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis

Thériault, S., Dina, C., Messika-Zeitoun, D., Le Scouarnec, S., Capoulade, R., Gaudreault, N., Rigade, S., Li, Z., Simonet, F., Lamontagne, M., et al. (2019) · Circulation: Genomic and Precision Medicine

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 90

RNA expression profile of calcified bicuspid, tricuspid, and normal human aortic valves by RNA sequencing

Guauque-Olarte, S., Droit, A., Tremblay-Marchand, J., Gaudreault, N., Kalavrouziotis, D., Dagenais, F., Seidman, J. G., Body, S. C., Pibarot, P., Mathieu, P., et al. (2016) · Physiological Genomics

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment Approaches

Cited by 82

Calcium Signaling Pathway Genes RUNX2 and CACNA1C Are Associated With Calcific Aortic Valve Disease

Guauque-Olarte, S., Messika-Zeitoun, D., Droit, A., Lamontagne, M., Tremblay-Marchand, J., Lavoie-Charland, E., Gaudreault, N., Arsenault, B. J., Dubé, M.-P., Tardif, J.-C., et al. (2015) · Circulation: Cardiovascular Genetics

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 72

Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation

Thériault, S., Li, Z., Abner, E., Luan, J., Manikpurage, H. D., Houessou, U., Zamani, P., Briend, M., Estonian Biobank Research Team, Boudreau, D. K., et al. (2024) · Nature Communications

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 49

Phenome-wide analyses establish a specific association between aortic valve PALMD expression and calcific aortic valve stenosis

Li, Z., Gaudreault, N., Arsenault, B. J., Mathieu, P., Bossé, Y., & Thériault, S. (2020) · Communications Biology

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 23

Enhancer-associated aortic valve stenosis risk locus 1p21.2 alters NFATC2 binding site and promotes fibrogenesis

Chignon, A., Rosa, M., Boulanger, M.-C., Argaud, D., Devillers, R., Bon-Baret, V., Mkannez, G., Li, Z., Rufiange, A., Gaudreault, N., et al. (2021) · iScience

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 18

Transcriptomic signatures of calcific aortic valve stenosis severity in human tricuspid and bicuspid aortic valves

Houessou, U., Zamani, P., Manikpurage, H. D., Li, Z., Gaudreault, N., Dahmene, M., Dagenais, F., Couture, C., Clavel, M.-A., Pibarot, P., et al. (2025) · JACC: Basic to Translational Science

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment Approaches

Cited by 11

A transcriptomic approach to sex differences in calcific aortic valve stenosis in patients with a tricuspid aortic valve

Le Nezet, E., Tam, R., Li, Z., Gaudreault, N., Mathieu, P., Côté, N., Guisle, I., Thériault, S., Bossé, Y., & Clavel, M.-A. (2025) · CJC Open

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment Approaches

Cited by 5

Aortic valve-specific genes dysregulated in calcific aortic valve stenosis as potential biomarkers and therapeutic targets

Zamani, P., Houessou, U., Manikpurage, H. D., Li, Z., Dahmene, M., Gaudreault, N., Dagenais, F., Clavel, M.-A., Pibarot, P., Arsenault, B. J., et al. (2025) · Human Genetics and Genomics Advances

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment Approaches

Cited by 3

Sex-specific gene expression signatures of calcific aortic valve stenosis in a large collection of human tissues

Houessou, U., Zamani, P., Manikpurage, H. D., Li, Z., Gaudreault, N., Dahmene, M., Dagenais, F., Couture, C., Clavel, M.-A., Pibarot, P., et al. (2026) · Atherosclerosis

Cardiac Valve Diseases and TreatmentsGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Cited by 1

CONTEXT-DEPENDENT AORTIC VALVE EQTLS HIGHLIGHT POTENTIAL CAUSAL DRIVERS OF AORTIC VALVE STENOSIS

Zamani, P., Houessou, U., Li, Z., Gaudreault, N., Bossé, Y., & Thériault, S. (2026) · Atherosclerosis

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 0

Connecting proteomics and genomics to identify causal biomarkers specific for aortic valve stenosis

Zamani, P., Houessou, U., Manikpurage, H. D., Dahmene, M., Li, Z., Gaudreault, N., Clavel, M.-A., Pibarot, P., Mathieu, P., Arsenault, B. J., et al. (2025) · medRxiv

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 0