Shen, Min

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Anastasiou, D., Yu, Y., Israelsen, W. J., Jiang, J.-K., Boxer, M. B., Hong, B. S., Tempel, W., Dimov, S., Shen, M., Jha, A., et al. (2012) · Nature Chemical Biology

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 816

Rational selection of training and test sets for the development of validated QSAR models

Golbraikh, A., Shen, M., Xiao, Z., Xiao, Y.-D., Lee, K.-H., & Tropsha, A. (2003) · Journal of Computer-Aided Molecular Design

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 712

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

Pacold, M. E., Brimacombe, K. R., Chan, S. H., Rohde, J. M., Lewis, C. A., Swier, L. J. Y. M., Possemato, R., Chen, W. W., Sullivan, L. B., Fiske, B. P., et al. (2016) · Nature Chemical Biology

Cancer, Hypoxia, and MetabolismBiochemical and Molecular Research

Cited by 553

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

Najm, F. J., Madhavan, M., Zaremba, A., Shick, E., Karl, R. T., Factor, D. C., Miller, T. E., Nevin, Z. S., Kantor, C., Sargent, A., et al. (2015) · Nature

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 424

A Comprehensive Collection of Pain and Opioid Use Disorder Compounds for High-Throughput Screening and Artificial Intelligence-Driven Drug Discovery

Hu, X., Shinn, P., Itkin, Z., Ye, L., Zhang, Y.-Q., Shen, M., Ford-Scheimer, S., & Hall, M. D. (2024) · ACS Pharmacology & Translational Science

Computational Drug Discovery MethodsOpioid Use Disorder Treatment

Cited by 3