Moldawer, Lyle L.

Genomic responses in mouse models poorly mimic human inflammatory diseases

Seok, J., Warren, H. S., Cuenca, A. G., Mindrinos, M. N., Baker, H. V., Xu, W., Richards, D. R., McDonald-Smith, G. P., Gao, H., Hennessy, L., et al. (2013) · Proceedings of the National Academy of Sciences

Animal testing and alternativesImmune Response and Inflammation

Cited by 3,005

A network-based analysis of systemic inflammation in humans

Program, I. A. H. R. T. I. L. S. C. R., Calvano, S. E., Xiao, W., Richards, D. R., Felciano, R. M., Baker, H. V., Cho, R. J., Chen, R. O., Brownstein, B. H., Cobb, J. P., et al. (2005) · Nature

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 1,429

Persistent inflammation and immunosuppression: A common syndrome and new horizon for surgical intensive care

Gentile, L. F., Cuenca, A. G., Efron, P. A., Ang, D., Bihorac, A., McKinley, B. A., Moldawer, L. L., & Moore, F. A. (2012) · Journal of Trauma and Acute Care Surgery

Sepsis Diagnosis and TreatmentClinical Nutrition and Gastroenterology

Cited by 801

Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome

Mira, J. C., Gentile, L. F., Mathias, B. J., Efron, P. A., Brakenridge, S. C., Mohr, A. M., Moore, F. A., & Moldawer, L. L. (2017) · Critical Care Medicine

Sepsis Diagnosis and TreatmentInflammation biomarkers and pathways

Cited by 526

MySurgeryRisk: development and validation of a machine-learning risk algorithm for major complications and death after surgery.

Bihorac, A., Ozrazgat-Baslanti, T., Ebadi, A., Motaei, A., Madkour, M., Pardalos, P. M., Lipori, G., Hogan, W. R., Efron, P. A., Moore, F., et al. (2019) · Annals of Surgery

Cardiac, Anesthesia and Surgical OutcomesMachine Learning in Healthcare

Cited by 377

Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man

Barber, A. E., Coyle, S. M., Marano, M. A., Fischer, E., Calvano, S. E., Fong, Y., Moldawer, L. L., & Lowry, S. F. (1993) · The Journal of Immunology

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 285

Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy

Horiguchi, H., Loftus, T. J., Hawkins, R. B., Raymond, S. L., Stortz, J. A., Hollen, M. K., Weiss, B. P., Miller, E. S., Bihorac, A., Larson, S. D., et al. (2018) · Frontiers in Immunology

Sepsis Diagnosis and TreatmentInflammation biomarkers and pathways

Cited by 164

Cachexia and the acute-phase protein response in inflammation are regulated by interleukin-6

Oldenburg, H. S. A., Rogy, M. A., Lazarus, D. D., van Zee, K. J., Keeler, B. P., Chizzonite, R. A., Lowry, S. F., & Moldawer, L. L. (1993) · European Journal of Immunology

Cytokine Signaling Pathways and InteractionsNutrition and Health in Aging

Cited by 155

Human transcriptome array for high-throughput clinical studies

Xu, W., Seok, J., Mindrinos, M. N., Schweitzer, A. C., Jiang, H., Wilhelmy, J., Clark, T. A., Kapur, K., Xing, Y., Faham, M., et al. (2011) · Proceedings of the National Academy of Sciences

Gene expression and cancer classificationGenomics and Phylogenetic Studies

Cited by 124

Interleukin-1 receptor blockade does not affect endotoxin-induced changes in plasma thyroid hormone and thyrotropin concentrations in man

van der Poll, T., Van Zee, K. J., Endert, E., Coyle, S. M., Stiles, D. M., Pribble, J. P., Catalano, M. A., Moldawer, L. L., & Lowry, S. F. (1995) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 85

Inhibition of tumor necrosis factor‐α attenuates wound breaking strength in rats

Lee, R. H., Efron, D. T., Tantry, U., Stuelten, C., Moldawer, L. L., Abouhamze, A., & Barbul, A. (2000) · Wound Repair and Regeneration

Wound Healing and TreatmentsLiver physiology and pathology

Cited by 63

Persistently Elevated Glucagon-Like Peptide-1 Levels among Critically Ill Surgical Patients after Sepsis and Development of Chronic Critical Illness and Dismal Long-Term Outcomes

Brakenridge, S. C., Moore, F. A., Mercier, N. R., Cox, M., Wu, Q., Moldawer, L. L., Mohr, A. M., Efron, P. A., & Smith, S. R. (2019) · Journal of the American College of Surgeons

Sepsis Diagnosis and TreatmentHyperglycemia and glycemic control in critically ill and hospitalized patients

Cited by 46