Boeckx, Bram

Phenotype molding of stromal cells in the lung tumor microenvironment

Lambrechts, D., Wauters, E., Boeckx, B., Aibar, S., Nittner, D., Burton, O., Bassez, A., Decaluwé, H., Pircher, A., Van den Eynde, K., et al. (2018) · Nature Medicine

Single-cell and spatial transcriptomicsCancer Immunotherapy and Biomarkers

Cited by 1,648

A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer

Bassez, A., Vos, H., Van Dyck, L., Floris, G., Arijs, I., Desmedt, C., Boeckx, B., Vanden Bempt, M., Nevelsteen, I., Lambein, K., et al. (2021) · Nature Medicine

Cancer Immunotherapy and BiomarkersBreast Cancer Treatment Studies

Cited by 867

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

Cantelmo, A. R., Conradi, L.-C., Brajic, A., Goveia, J., Kalucka, J., Pircher, A., Chaturvedi, P., Hol, J., Thienpont, B., Teuwen, L.-A., et al. (2016) · Cancer Cell

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

Cited by 659

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

Thienpont, B., Steinbacher, J., Zhao, H., D’Anna, F., Kuchnio, A., Ploumakis, A., Ghesquière, B., Van Dyck, L., Boeckx, B., Schoonjans, L., et al. (2016) · Nature

Epigenetics and DNA MethylationCancer, Hypoxia, and Metabolism

Cited by 635

Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity

Vanderbeke, L., Van Mol, P., Van Herck, Y., De Smet, F., Humblet-Baron, S., Martinod, K., Antoranz, A., Arijs, I., Boeckx, B., Bosisio, F. M., et al. (2021) · Nature Communications

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 247

Developing Organoids from Ovarian Cancer as Experimental and Preclinical Models

Maenhoudt, N., Defraye, C., Boretto, M., Jan, Z., Heremans, R., Boeckx, B., Hermans, F., Arijs, I., Cox, B., Van Nieuwenhuysen, E., et al. (2020) · Stem Cell Reports

Ovarian cancer diagnosis and treatmentCancer Cells and Metastasis

Cited by 186

Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching

De Smedt, L., Palmans, S., Andel, D., Govaere, O., Boeckx, B., Smeets, D., Galle, E., Wouters, J., Barras, D., Suffiotti, M., et al. (2017) · British Journal of Cancer

Cancer Cells and MetastasisColorectal Cancer Treatments and Studies

Cited by 163

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

Goveia, J., Rohlenova, K., Taverna, F., Treps, L., Conradi, L.-C., Pircher, A., Geldhof, V., de Rooij, L. P. M. H., Kalucka, J., Sokol, L., et al. (2020) · Cancer Cell

Angiogenesis and VEGF in CancerSingle-cell and spatial transcriptomics

Cited by 125

Single-cell Transcriptomics Uncover a Novel Role of Myeloid Cells and T-lymphocytes in the Fibrotic Microenvironment in Peyronie’s Disease

Milenkovic, U., Boeckx, B., Lambrechts, D., Janky, R., Hatzichristodoulou, G., van Renterghem, K., Gevaert, T., Cellek, S., Bivalacqua, T. J., De Ridder, D., et al. (2022) · European Urology Focus

Dupuytren's Contracture and TreatmentsUrological Disorders and Treatments

Cited by 14