Hewitt, Philip

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, P., Hewitt, N. J., Albrecht, U., Andersen, M. E., Ansari, N., Bhattacharya, S., Bode, J. G., Bolleyn, J., Borner, C., Böttger, J., et al. (2013) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 1,280

Liver microphysiological systems development guidelines for safety risk assessment in the pharmaceutical industry

Baudy, A. R., Otieno, M. A., Hewitt, P., Gan, J., Roth, A., Keller, D., Sura, R., Van Vleet, T. R., & Proctor, W. R. (2020) · Lab on a Chip

3D Printing in Biomedical ResearchDrug-Induced Hepatotoxicity and Protection

Cited by 150

Towards in vitro models for reducing or replacing the use of animals in drug testing

Stresser, D. M., Kopec, A. K., Hewitt, P., Hardwick, R. N., Van Vleet, T. R., Mahalingaiah, P. K. S., O’Connell, D., Jenkins, G. J., David, R., Graham, J., et al. (2023) · Nature Biomedical Engineering

Animal testing and alternatives3D Printing in Biomedical Research

Cited by 94

https://www.altex.org/index.php/altex/article/view/1339

Krebs, A., Waldmann, T., Wilks, M. F., van Vugt-Lussenburg, B. M. A., van der Burg, B., Terron, A., Steger-Hartmann, T., Ruegg, J., Rovida, C., Pedersen, E., et al. (2019) · ALTEX

Animal testing and alternativesAgricultural safety and regulations

Cited by 77

Microphysiological Systems Evaluation: Experience of TEX-VAL Tissue Chip Testing Consortium

Rusyn, I., Sakolish, C., Kato, Y., Stephan, C., Vergara, L., Hewitt, P., Bhaskaran, V., Davis, M., Hardwick, R. N., Ferguson, S. S., et al. (2022) · Toxicological Sciences

3D Printing in Biomedical ResearchAnimal testing and alternatives

Cited by 43

Considerations from an international regulatory and pharmaceutical industry (IQ MPS affiliate) workshop on the standardization of complex in vitro models in drug development

Tomlinson, L., Ramsden, D., Leite, S. B., Beken, S., Bonzo, J. A., Brown, P., Candarlioglu, P. L., Chan, T. S., Chen, E., Choi, C. K., et al. (2024) · Advanced Biology

3D Printing in Biomedical ResearchBiomedical Ethics and Regulation

Cited by 33

Comparative Analysis of Proximal Tubule Cell Sources for In Vitro Studies of Renal Proximal Tubule Toxicity

Sakolish, C., Tsai, H.-H. D., Lin, H.-C., Bajaj, P., Villenave, R., Ferguson, S. S., Stanko, J. P., Becker, R. A., Hewitt, P., Chiu, W. A., et al. (2025) · Biomedicines

Animal testing and alternativesAcute Kidney Injury Research

Cited by 11