Klaus, Christine

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells

Knutson, S. K., Wigle, T. J., Warholic, N. M., Sneeringer, C. J., Allain, C. J., Klaus, C. R., Sacks, J. D., Raimondi, A., Majer, C. R., Song, J., et al. (2012) · Nature Chemical Biology

Epigenetics and DNA MethylationCancer-related gene regulation

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Potent inhibition of DOT1L as treatment of MLL-fusion leukemia

Daigle, S. R., Olhava, E. J., Therkelsen, C. A., Basavapathruni, A., Jin, L., Boriack-Sjodin, P. A., Allain, C. J., Klaus, C. R., Raimondi, A., Scott, M. P., et al. (2013) · Blood

Acute Myeloid Leukemia ResearchAcute Lymphoblastic Leukemia research

Cited by 722

TREM2 triggers microglial density and age-related neuronal loss

Linnartz‐Gerlach, B., Bodea, L., Klaus, C., Ginolhac, A., Halder, R., Sinkkonen, L., Walter, J., Colonna, M., & Neumann, H. (2019) · Glia

Neuroinflammation and Neurodegeneration MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 104

Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor

Mitchell, L. H., Boriack-Sjodin, P. A., Smith, S., Thomenius, M., Rioux, N., Munchhof, M., Mills, J. E., Klaus, C., Totman, J., Riera, T. V., et al. (2016) · ACS Medicinal Chemistry Letters

Cancer-related gene regulationEpigenetics and DNA Methylation

Cited by 91