Wai, Timothy

The i -AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

Anand, R., Wai, T., Baker, M. J., Kladt, N., Schauss, A. C., Rugarli, E., & Langer, T. (2014) · Journal of Cell Biology

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 812

Distinct fission signatures predict mitochondrial degradation or biogenesis.

Kleele, T., Rey, T., Winter, J., Zaganelli, S., Mahecic, D., Perreten Lambert, H., Ruberto, F. P., Nemir, M., Wai, T., Pedrazzini, T., et al. (2021) · Nature

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 794

Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice

Wai, T., García-Prieto, J., Baker, M. J., Merkwirth, C., Benit, P., Rustin, P., Rupérez, F. J., Barbas, C., Ibañez, B., & Langer, T. (2015) · Science

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 551

Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation

Hartmann, B., Wai, T., Hu, H., MacVicar, T., Musante, L., Fischer-Zirnsak, B., Stenzel, W., Gräf, R., van den Heuvel, L., Ropers, H.-H., et al. (2016) · eLife

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 124