Elsworth, Benjamin

The MR-Base platform supports systematic causal inference across the human phenome

Hemani, G., Zheng, J., Elsworth, B., Wade, K. H., Haberland, V., Baird, D., Laurin, C., Burgess, S., Bowden, J., Langdon, R., et al. (2018) · eLife

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 7,959

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

Zheng, J., Erzurumluoglu, A. M., Elsworth, B. L., Kemp, J. P., Howe, L., Haycock, P. C., Hemani, G., Tansey, K., Laurin, C., Early Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium, et al. (2017) · Bioinformatics

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 869

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases.

Zheng, J., Haberland, V., Baird, D., Walker, V., Haycock, P., Hurle, M., Gutteridge, A., Erola, P., Liu, Y., Luo, S., et al. (2019) · Nature Genetics

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 812

Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer

Cazet, A. S., Hui, M. N., Elsworth, B. L., Wu, S. Z., Roden, D., Chan, C.-L., Skhinas, J. N., Collot, R., Yang, J., Harvey, K., et al. (2018) · Nature Communications

Hedgehog Signaling Pathway StudiesCancer Cells and Metastasis

Cited by 437

Can the impact of childhood adiposity on disease risk be reversed? A Mendelian randomization study.

Richardson, T. G., Sanderson, E., Elsworth, B., Tilling, K., & Davey Smith, G. (2019) · BMJ

Genetic Associations and EpidemiologyBirth, Development, and Health

Cited by 321

Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation

Richardson, T. G., Leyden, G. M., Wang, Q., Bell, J. A., Elsworth, B., Davey Smith, G., & Holmes, M. V. (2022) · PLOS Biology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 304

Analysis-ready VCF at Biobank scale using Zarr

Czech, E., Millar, T. R., Tyler, W., White, T., Elsworth, B., Guez, J., Hancox, J., Jeffery, B., Karczewski, K. J., Miles, A., et al. (2024) · GigaScience

Scientific Computing and Data ManagementGenomics and Phylogenetic Studies

Cited by 8