Whitelaw, Murray L.

Asparagine Hydroxylation of the HIF Transactivation Domain: A Hypoxic Switch

Lando, D., Peet, D. J., Whelan, D. A., Gorman, J. J., & Whitelaw, M. L. (2002) · Science

Cancer, Hypoxia, and MetabolismKruppel-like factors research

Cited by 1,558

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

Lando, D., Peet, D. J., Gorman, J. J., Whelan, D. A., Whitelaw, M. L., & Bruick, R. K. (2002) · Genes & Development

Cancer, Hypoxia, and MetabolismMetal-Catalyzed Oxygenation Mechanisms

Cited by 1,550

Functional Interference between Hypoxia and Dioxin Signal Transduction Pathways: Competition for Recruitment of the Arnt Transcription Factor

Gradin, K., McGuire, J., Wenger, R. H., Kvietikova, I., Whitelaw, M. L., Toftgård, R., Tora, L., Gassmann, M., & Poellinger, L. (1996) · Molecular and Cellular Biology

Cancer, Hypoxia, and MetabolismToxic Organic Pollutants Impact

Cited by 470

A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors

Andersson, P., McGuire, J., Rubio, C., Gradin, K., Whitelaw, M. L., Pettersson, S., Hanberg, A., & Poellinger, L. (2002) · Proceedings of the National Academy of Sciences

Toxic Organic Pollutants ImpactPharmacogenetics and Drug Metabolism

Cited by 310

bHLH-PAS proteins in cancer

Bersten, D. C., Sullivan, A. E., Peet, D. J., & Whitelaw, M. L. (2013) · Nature Reviews Cancer

Cancer-related Molecular PathwaysChromatin Remodeling and Cancer

Cited by 267

Cell-specific Regulation of Hypoxia-inducible Factor (HIF)-1α and HIF-2α Stabilization and Transactivation in a Graded Oxygen Environment

Bracken, C. P., Fedele, A. O., Linke, S., Balrak, W., Lisy, K., Whitelaw, M. L., & Peet, D. J. (2006) · Journal of Biological Chemistry

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 222

Definition of a Minimal Domain of the Dioxin Receptor That Is Associated with Hsp90 and Maintains Wild Type Ligand Binding Affinity and Specificity

Coumailleau, P., Poellinger, L., Gustafsson, J.-Å., & Whitelaw, M. L. (1995) · Journal of Biological Chemistry

Toxic Organic Pollutants ImpactHeat shock proteins research

Cited by 172

Definition of a Dioxin Receptor Mutant That Is a Constitutive Activator of Transcription

McGuire, J., Okamoto, K., Whitelaw, M. L., Tanaka, H., & Poellinger, L. (2001) · Journal of Biological Chemistry

Toxic Organic Pollutants ImpactPeroxisome Proliferator-Activated Receptors

Cited by 102

Amino Acid Substitutions in the Aryl Hydrocarbon Receptor Ligand Binding Domain Reveal YH439 As an Atypical AhR Activator

Whelan, F., Hao, N., Furness, S. G. B., Whitelaw, M. L., & Chapman-Smith, A. (2010) · Molecular Pharmacology

Toxic Organic Pollutants ImpactPharmacogenetics and Drug Metabolism

Cited by 22

Molecular characterisation of rare loss-of-function NPAS3 and NPAS4 variants identified in individuals with neurodevelopmental disorders

Rossi, J. J., Rosenfeld, J. A., Chan, K. M., Streff, H., Nankivell, V., Peet, D. J., Whitelaw, M. L., & Bersten, D. C. (2021) · Scientific Reports

Genetics and Neurodevelopmental DisordersGenomics and Rare Diseases

Cited by 17