Craessaerts, Katleen

A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

De Strooper, B., Annaert, W., Cupers, P., Saftig, P., Craessaerts, K., Mumm, J. S., Schroeter, E. H., Schrijvers, V., Wolfe, M. S., Ray, W. J., et al. (1999) · Nature

Alzheimer's disease research and treatmentsDevelopmental Biology and Gene Regulation

Cited by 2,100

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

De Strooper, B., Saftig, P., Craessaerts, K., Vanderstichele, H., Guhde, G., Annaert, W., Von Figura, K., & Van Leuven, F. (1998) · Nature

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 1,818

Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer’s Disease

Chen, W.-T., Lu, A., Craessaerts, K., Pavie, B., Sala Frigerio, C., Corthout, N., Qian, X., Laláková, J., Kühnemund, M., Voytyuk, I., et al. (2020) · Cell

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 949

The Disintegrin/Metalloproteinase ADAM10 Is Essential for the Establishment of the Brain Cortex

Jorissen, E., Prox, J., Bernreuther, C., Weber, S., Schwanbeck, R., Serneels, L., Snellinx, A., Craessaerts, K., Thathiah, A., Tesseur, I., et al. (2010) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 363

Analysis of the γ-secretase interactome and validation of its association with tetraspanin-enriched microdomains

Wakabayashi, T., Craessaerts, K., Bammens, L., Bentahir, M., Borgions, F., Herdewijn, P., Staes, A., Timmerman, E., Vandekerckhove, J., Rubinstein, E., et al. (2009) · Nature Cell Biology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 135