Vincent, Emma E.

PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer

Dupuy, F., Tabariès, S., Andrzejewski, S., Dong, Z., Blagih, J., Annis, M. G., Omeroglu, A., Gao, D., Leung, S., Amir, E., et al. (2015) · Cell Metabolism

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 558

Loss of the Tumor Suppressor LKB1 Promotes Metabolic Reprogramming of Cancer Cells via HIF-1α

Faubert, B., Vincent, E. E., Griss, T., Samborska, B., Izreig, S., Svensson, R. U., Mamer, O. A., Avizonis, D., Shackelford, D. B., Shaw, R. J., et al. (2014) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 278

The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway

Carbonneau, M., M. Gagné, L., Lalonde, M.-E., Germain, M.-A., Motorina, A., Guiot, M.-C., Secco, B., Vincent, E. E., Tumber, A., Hulea, L., et al. (2016) · Nature Communications

Cancer, Hypoxia, and MetabolismPI3K/AKT/mTOR signaling in cancer

Cited by 180

Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer

Yarmolinsky, J., Bull, C. J., Vincent, E. E., Robinson, J., Walther, A., Smith, G. D., Lewis, S. J., Relton, C. L., & Martin, R. M. (2020) · JAMA

Cancer, Lipids, and MetabolismBRCA gene mutations in cancer

Cited by 124

GAM: a web-service for integrated transcriptional and metabolic network analysis

Sergushichev, A. A., Loboda, A. A., Jha, A. K., Vincent, E. E., Driggers, E. M., Jones, R. G., Pearce, E. J., & Artyomov, M. N. (2016) · Nucleic Acids Research

Bioinformatics and Genomic NetworksMicrobial Metabolic Engineering and Bioproduction

Cited by 94

Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation

Martin, S., Tyrrell, J., Thomas, E. L., Bown, M. J., Wood, A. R., Beaumont, R. N., Tsoi, L. C., Stuart, P. E., Elder, J. T., Law, P., et al. (2022) · eLife

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 43