Millard, Christopher J.

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

Millard, C. J., Watson, P. J., Celardo, I., Gordiyenko, Y., Cowley, S. M., Robinson, C. V., Fairall, L., & Schwabe, J. W. R. (2013) · Molecular Cell

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 396

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

Watson, P. J., Millard, C. J., Riley, A. M., Robertson, N. S., Wright, L. C., Godage, H. Y., Cowley, S. M., Jamieson, A. G., Potter, B. V. L., & Schwabe, J. W. R. (2016) · Nature Communications

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 244

Targeting Class I Histone Deacetylases in a “Complex” Environment

Millard, C. J., Watson, P. J., Fairall, L., & Schwabe, J. W. R. (2017) · Trends in Pharmacological Sciences

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 180

PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes

Smalley, J. P., Adams, G. E., Millard, C. J., Song, Y., Norris, J. K. S., Schwabe, J. W. R., Cowley, S. M., & Hodgkinson, J. T. (2020) · Chemical Communications

Protein Degradation and InhibitorsHistone Deacetylase Inhibitors Research

Cited by 121

The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure

Turnbull, R. E., Fairall, L., Saleh, A., Kelsall, E., Morris, K. L., Ragan, T. J., Savva, C. G., Chandru, A., Millard, C. J., Makarova, O. V., et al. (2020) · Nature Communications

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 108

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor

Zhang, L., Fairall, L., Goult, B. T., Calkin, A. C., Hong, C., Millard, C. J., Tontonoz, P., & Schwabe, J. W. R. (2011) · Genes & Development

Ubiquitin and proteasome pathwaysCholesterol and Lipid Metabolism

Cited by 86

Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: The N-Terminal Region of CCR3 Bound to CCL11/Eotaxin-1

Millard, C. J., Ludeman, J. P., Canals, M., Bridgford, J. L., Hinds, M. G., Clayton, D. J., Christopoulos, A., Payne, R. J., & Stone, M. J. (2014) · Structure

Chemokine receptors and signalingReceptor Mechanisms and Signaling

Cited by 75