Harrington, Lucas B.

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

Chen, J. S., Ma, E., Harrington, L. B., Da Costa, M., Tian, X., Palefsky, J. M., & Doudna, J. A. (2018) · Science

CRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniques

Cited by 4,507

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

Chen, J. S., Dagdas, Y. S., Kleinstiver, B. P., Welch, M. M., Sousa, A. A., Harrington, L. B., Sternberg, S. H., Joung, J. K., Yildiz, A., & Doudna, J. A. (2017) · Nature

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,168

CasX enzymes comprise a distinct family of RNA-guided genome editors

Liu, J.-J., Orlova, N., Oakes, B. L., Ma, E., Spinner, H. B., Baney, K. L. M., Chuck, J., Tan, D., Knott, G. J., Harrington, L. B., et al. (2019) · Nature

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 446

A Thermostable Cas9 with Increased Lifetime in Human Plasma

Harrington, L. B., Paez-Espino, D., Staahl, B. T., Chen, J. S., Ma, E., Kyrpides, N. C., & Doudna, J. A. (2017) · Nature Communications

CRISPR and Genetic EngineeringRNA regulation and disease

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