Tokunaga, Fuminori

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

Ikeda, F., Deribe, Y. L., Skånland, S. S., Stieglitz, B., Grabbe, C., Franz-Wachtel, M., van Wijk, S. J. L., Goswami, P., Nagy, V., Terzic, J., et al. (2011) · Nature

NF-κB Signaling PathwaysUbiquitin and proteasome pathways

Cited by 745

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

Tokunaga, F., Nakagawa, T., Nakahara, M., Saeki, Y., Taniguchi, M., Sakata, S.-I., Tanaka, K., Nakano, H., & Iwai, K. (2011) · Nature

NF-κB Signaling PathwaysUbiquitin and proteasome pathways

Cited by 609

Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction

Inn, K.-S., Gack, M. U., Tokunaga, F., Shi, M., Wong, L.-Y., Iwai, K., & Jung, J. U. (2011) · Molecular Cell

interferon and immune responsesImmune Response and Inflammation

Cited by 209

Identification of the ubiquitin–protein ligase that recognizes oxidized IRP2

Yamanaka, K., Ishikawa, H., Megumi, Y., Tokunaga, F., Kanie, M., Rouault, T. A., Morishima, I., Minato, N., Ishimori, K., & Iwai, K. (2003) · Nature Cell Biology

Ubiquitin and proteasome pathwaysIron Metabolism and Disorders

Cited by 181

Interplay between protein acetylation and ubiquitination controls MCL1 protein stability

Shimizu, K., Gi, M., Suzuki, S., North, B. J., Watahiki, A., Fukumoto, S., Asara, J. M., Tokunaga, F., Wei, W., & Inuzuka, H. (2021) · Cell Reports

Ubiquitin and proteasome pathwaysCell death mechanisms and regulation

Cited by 62

The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3

Kumanomidou, T., Nishio, K., Takagi, K., Nakagawa, T., Suzuki, A., Yamane, T., Tokunaga, F., Iwai, K., Murakami, A., Yoshida, Y., et al. (2015) · PLOS ONE

Ubiquitin and proteasome pathwaysEnzyme Structure and Function

Cited by 21

Linear Polyubiquitin Chain Modification of TDP-43-Positive Neuronal Cytoplasmic Inclusions in Amyotrophic Lateral Sclerosis

Nakayama, Y., Tsuji, K., Ayaki, T., Mori, M., Tokunaga, F., & Ito, H. (2020) · Journal of Neuropathology & Experimental Neurology

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 18