Houck, Keith A.

Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms.

Houck, K. A., Leung, D. W., Rowland, A. M., Winer, J., & Ferrara, N. (1992) · Journal of Biological Chemistry

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 1,127

Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment

Wetmore, B. A., Wambaugh, J. F., Ferguson, S. S., Sochaski, M. A., Rotroff, D. M., Freeman, K., Clewell, H. J., Dix, D. J., Andersen, M. E., Houck, K. A., et al. (2012) · Toxicological Sciences

Animal testing and alternativesCarcinogens and Genotoxicity Assessment

Cited by 415

The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology

Richard, A. M., Huang, R., Waidyanatha, S., Shinn, P., Collins, B. J., Thillainadarajah, I., Grulke, C. M., Williams, A. J., Lougee, R. R., Judson, R. S., et al. (2021) · Chemical Research in Toxicology

Computational Drug Discovery MethodsEnvironmental Toxicology and Ecotoxicology

Cited by 323

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space

Judson, R., Houck, K., Martin, M., Richard, A. M., Knudsen, T. B., Shah, I., Little, S., Wambaugh, J., Woodrow Setzer, R., Kothya, P., et al. (2016) · Toxicological Sciences

Animal testing and alternativesEnvironmental Toxicology and Ecotoxicology

Cited by 232

Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms

Kleinstreuer, N. C., Yang, J., Berg, E. L., Knudsen, T. B., Richard, A. M., Martin, M. T., Reif, D. M., Judson, R. S., Polokoff, M., Dix, D. J., et al. (2014) · Nature Biotechnology

Computational Drug Discovery MethodsAnimal testing and alternatives

Cited by 211

Evaluation of 147 perfluoroalkyl substances for immunotoxic and other (patho)physiological activities through phenotypic screening of human primary cells

Houck, K. (2022) · ALTEX

Per- and polyfluoroalkyl substances researchImmunotoxicology and immune responses

Cited by 20