Warmuth, Markus

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Barretina, J., Caponigro, G., Stransky, N., Venkatesan, K., Margolin, A. A., Kim, S., Wilson, C. J., Lehár, J., Kryukov, G. V., Sonkin, D., et al. (2012) · Nature

Cancer Genomics and DiagnosticsComputational Drug Discovery Methods

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Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Chen, Y.-N. P., LaMarche, M. J., Chan, H. M., Fekkes, P., Garcia-Fortanet, J., Acker, M. G., Antonakos, B., Chen, C. H.-T., Chen, Z., Cooke, V. G., et al. (2016) · Nature

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 925

Ba/F3 cells and their use in kinase drug discovery

Warmuth, M., Kim, S., Gu, X.-J., Xia, G., & Adrián, F. (2007) · Current Opinion in Oncology

Cancer Mechanisms and TherapyProtein Kinase Regulation and GTPase Signaling

Cited by 240

Mining the CRBN target space redefines rules for molecular glue-induced neosubstrate recognition

Petzold, G., Gainza, P., Annunziato, S., Lamberto, I., Trenh, P., McAllister, L. A., DeMarco, B., Schwander, L., Bunker, R. D., Zlotosch, M., et al. (2025) · Science

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 117

Mining the CRBN Target Space Redefines Rules for Molecular Glue-induced Neosubstrate Recognition

Petzold, G., Gainza, P., Annunziato, S., Lamberto, I., Trenh, P., McAllister, L., Demarco, B., Schwander, L., Bunker, R. D., Zlotosch, M., et al. (2024) · Science

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 117

Abstract LB422: Selective targeting of CDK2 using molecular glue degraders for the treatment of HR-positive/HER2-negative breast cancer

Gkountela, S., Tahaney, W., Vafeiadou, V., Bianda, C., Cheeseman, L., Singh, A., Diesslin, A., Schillo, M., Nguyen, S., Moccia, L., et al. (2025) · Cancer Research

Protein Degradation and InhibitorsAdvanced Breast Cancer Therapies

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