Schenone, Monica

Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells

Krönke, J., Udeshi, N. D., Narla, A., Grauman, P., Hurst, S. N., McConkey, M., Svinkina, T., Heckl, D., Comer, E., Li, X., et al. (2014) · Science

Protein Degradation and InhibitorsMultiple Myeloma Research and Treatments

Cited by 1,879

WRN helicase is a synthetic lethal target in microsatellite unstable cancers

Chan, E. M., Shibue, T., McFarland, J. M., Gaeta, B., Ghandi, M., Dumont, N., Gonzalez, A., McPartlan, J. S., Li, T., Zhang, Y., et al. (2019) · Nature

Genetic factors in colorectal cancerDNA Repair Mechanisms

Cited by 458

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

Rusu, V., Hoch, E., Mercader, J. M., Tenen, D. E., Gymrek, M., Hartigan, C. R., DeRan, M., von Grotthuss, M., Fontanillas, P., Spooner, A., et al. (2017) · Cell

Genetic Associations and EpidemiologyMetabolism, Diabetes, and Cancer

Cited by 152

Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6

McCoull, W., Cheung, T., Anderson, E., Barton, P., Burgess, J., Byth, K., Cao, Q., Castaldi, M. P., Chen, H., Chiarparin, E., et al. (2018) · ACS Chemical Biology

Protein Degradation and InhibitorsLymphoma Diagnosis and Treatment

Cited by 139

Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation

Basak, A., Munschauer, M., Lareau, C. A., Montbleau, K. E., Ulirsch, J. C., Hartigan, C. R., Schenone, M., Lian, J., Wang, Y., Huang, Y., et al. (2020) · Nature Genetics

Hemoglobinopathies and Related DisordersRNA Research and Splicing

Cited by 105

Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics

de Waal, L., Lewis, T. A., Rees, M. G., Tsherniak, A., Wu, X., Choi, P. S., Gechijian, L., Hartigan, C., Faloon, P. W., Hickey, M. J., et al. (2016) · Nature Chemical Biology

Phosphodiesterase function and regulationComputational Drug Discovery Methods

Cited by 96

SHIFTR enables the unbiased identification of proteins bound to specific RNA regions in live cells

Aydin, J., Gabel, A., Zielinski, S., Ganskih, S., Schmidt, N., Hartigan, C. R., Schenone, M., Carr, S. A., & Munschauer, M. (2024) · Nucleic Acids Research

RNA Research and SplicingBiotin and Related Studies

Cited by 12

SHIFTR enables the unbiased and multiplexed identification of proteins bound to specific RNA regions in live cells

Aydin, J., Gabel, A., Zielinski, S., Ganskih, S., Schmidt, N., Hartigan, C. R., Schenone, M., Carr, S. A., & Munschauer, M. (2023) · Nucleic Acids Research

RNA Research and SplicingBiotin and Related Studies

Cited by 12