Andrews, Nancy C.

Disorders of Iron Metabolism

Andrews, N. C. (1999) · New England Journal of Medicine

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 2,130

Balancing Acts

Hentze, M. W., Muckenthaler, M. U., & Andrews, N. C. (2004) · Cell

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 1,736

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

Donovan, A., Brownlie, A., Zhou, Y., Shepard, J., Pratt, S. J., Moynihan, J., Paw, B. H., Drejer, A., Barut, B., Zapata, A., et al. (2000) · Nature

Iron Metabolism and DisordersTrace Elements in Health

Cited by 1,667

The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis

Donovan, A., Lima, C. A., Pinkus, J. L., Pinkus, G. S., Zon, L. I., Robine, S., & Andrews, N. C. (2005) · Cell Metabolism

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 1,275

Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

Fleming, M. D., Trenor, C. C., Su, M. A., Foernzler, D., Beier, D. R., Dietrich, W. F., & Andrews, N. C. (1997) · Nature Genetics

Iron Metabolism and DisordersTrace Elements in Health

Cited by 1,159

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

Babitt, J. L., Huang, F. W., Wrighting, D. M., Xia, Y., Sidis, Y., Samad, T. A., Campagna, J. A., Chung, R. T., Schneyer, A. L., Woolf, C. J., et al. (2006) · Nature Genetics

Iron Metabolism and DisordersPlant Micronutrient Interactions and Effects

Cited by 1,026

Interleukin-6 induces hepcidin expression through STAT3

Wrighting, D. M., & Andrews, N. C. (2006) · Blood

Iron Metabolism and DisordersCytokine Signaling Pathways and Interactions

Cited by 983

Nramp 2 is mutated in the anemic Belgrade ( b ) rat: Evidence of a role for Nramp2 in endosomal iron transport

Fleming, M. D., Romano, M. A., Su, M. A., Garrick, L. M., Garrick, M. D., & Andrews, N. C. (1998) · Proceedings of the National Academy of Sciences

Iron Metabolism and DisordersTrace Elements in Health

Cited by 936

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

Finberg, K. E., Heeney, M. M., Campagna, D. R., Aydınok, Y., Pearson, H. A., Hartman, K. R., Mayo, M. M., Samuel, S. M., Strouse, J. J., Markianos, K., et al. (2008) · Nature Genetics

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 675

Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease

Weinstein, D. A., Roy, C. N., Fleming, M. D., Loda, M. F., Wolfsdorf, J. I., & Andrews, N. C. (2002) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 632

Forging a field: the golden age of iron biology.

Andrews, N. C. (2008) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 623

Transferrin receptor is necessary for development of erythrocytes and the nervous system

Levy, J. E., Jin, O., Fujiwara, Y., Kuo, F., & Andrews, N. (1999) · Nature Genetics

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 574

Autosomal-dominant hemochrom-atosis is associated with a mutation in the ferroportin (SLC11A3) gene

Montosi, G., Donovan, A., Totaro, A., Garuti, C., Pignatti, E., Cassanelli, S., Trenor, C. C., Gasparini, P., Andrews, N. C., & Pietrangelo, A. (2001) · Journal of Clinical Investigation

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 557

Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver

Gunshin, H., Fujiwara, Y., Custodio, A. O., DiRenzo, C., Robine, S., & Andrews, N. C. (2005) · Journal of Clinical Investigation

Iron Metabolism and DisordersTrace Elements in Health

Cited by 419

Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing.

Goswami, T., & Andrews, N. C. (2006) · Journal of Biological Chemistry

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 352

The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression

Schmidt, P. J., Toran, P. T., Giannetti, A. M., Bjorkman, P. J., & Andrews, N. C. (2008) · Cell Metabolism

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 345

Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis

Nicolas, G., Viatte, L., Lou, D.-Q., Bennoun, M., Beaumont, C., Kahn, A., Andrews, N. C., & Vaulont, S. (2003) · Nature Genetics

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 311

Iron-dependent regulation of the divalent metal ion transporter

Gunshin, H., Allerson, C. R., Polycarpou-Schwarz, M., Rofts, A., Rogers, J. T., Kishi, F., Hentze, M. W., Rouault, T. A., Andrews, N. C., & Hediger, M. A. (2001) · FEBS Letters

Iron Metabolism and DisordersTrace Elements in Health

Cited by 305

A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency

Jabara, H. H., Boyden, S. E., Chou, J., Ramesh, N., Massaad, M. J., Benson, H., Bainter, W., Fraulino, D., Rahimov, F., Sieff, C., et al. (2016) · Nature Genetics

Iron Metabolism and DisordersImmunodeficiency and Autoimmune Disorders

Cited by 279

Comparison of the Interactions of Transferrin Receptor and Transferrin Receptor 2 with Transferrin and the Hereditary Hemochromatosis Protein HFE

West, A. P., Bennett, M. J., Sellers, V. M., Andrews, N. C., Enns, C. A., & Bjorkman, P. J. (2000) · Journal of Biological Chemistry

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 257

Proinflammatory state, hepcidin, and anemia in older persons

Ferrucci, L., Semba, R. D., Guralnik, J. M., Ershler, W. B., Bandinelli, S., Patel, K. V., Sun, K., Woodman, R. C., Andrews, N. C., Cotter, R. J., et al. (2010) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 245

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice

Gardenghi, S., Ramos, P., Marongiu, M. F., Melchiori, L., Breda, L., Guy, E., Muirhead, K., Rao, N., Roy, C. N., Andrews, N. C., et al. (2010) · Journal of Clinical Investigation

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 220

Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice

Gunshin, H., Starr, C. N., DiRenzo, C., Fleming, M. D., Jin, J., Greer, E. L., Sellers, V. M., Galica, S. M., & Andrews, N. C. (2005) · Blood

Iron Metabolism and DisordersTrace Elements in Health

Cited by 188

Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation

Roy, C. N., Mak, H. H., Akpan, I., Losyev, G., Zurakowski, D., & Andrews, N. C. (2007) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 178