Shorter, James

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Prions as adaptive conduits of memory and inheritance

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C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy

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CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation

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Repetitive elements in aging and neurodegeneration

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Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3

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Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3

Cupo, R. R., Rizo, A. N., Braun, G. A., Tse, E., Chuang, E., Southworth, D. R., & Shorter, J. (2022) · Cell Reports

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Sequestration of TDP-43 216-414 Aggregates by Cytoplasmic Expression of the proSAAS Chaperone

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Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration

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