Lessard, Frédéric

Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation

Deschênes-Simard, X., Gaumont-Leclerc, M.-F., Bourdeau, V., Lessard, F., Moiseeva, O., Forest, V., Igelmann, S., Mallette, F. A., Saba-El-Leil, M. K., Meloche, S., et al. (2013) · Genes & Development

Telomeres, Telomerase, and SenescenceMelanoma and MAPK Pathways

Cited by 194

Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway

Lessard, F., Igelmann, S., Trahan, C., Huot, G., Saint-Germain, E., Mignacca, L., Del Toro, N., Lopes-Paciencia, S., Le Calvé, B., Montero, M., et al. (2018) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 174

A hydride transfer complex reprograms NAD metabolism and bypasses senescence

Igelmann, S., Lessard, F., Uchenunu, O., Bouchard, J., Fernandez-Ruiz, A., Rowell, M.-C., Lopes-Paciencia, S., Papadopoli, D., Fouillen, A., Ponce, K. J., et al. (2021) · Molecular Cell

Telomeres, Telomerase, and SenescenceSirtuins and Resveratrol in Medicine

Cited by 60

A model for the topology of active ribosomal RNA genes

Denissov, S., Lessard, F., Mayer, C., Stefanovsky, V., van Driel, M., Grummt, I., Moss, T., & Stunnenberg, H. G. (2011) · The EMBO Reports

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 58