Brown, Peter J
University of Toronto · Structural Genomics Consortium
7 papers on CoChatORCID 0000-0002-8454-0367
Most cited papers
- Verified
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ
Kliewer, S. A., Sundseth, S. S., Jones, S. A., Brown, P. J., Wisely, G. B., Koble, C. S., Devchand, P., Wahli, W., Willson, T. M., Lenhard, J. M., et al. (1997) · Proceedings of the National Academy of Sciences
Peroxisome Proliferator-Activated ReceptorsFatty Acid Research and Health
Cited by 2,164
- Verified
The PPARs: From Orphan Receptors to Drug Discovery
Willson, T. M., Brown, P. J., Sternbach, D. D., & Henke, B. R. (2000) · Journal of Medicinal Chemistry
Peroxisome Proliferator-Activated ReceptorsNuclear Receptors and Signaling
Cited by 1,816
- Verified
Molecular recognition of fatty acids by peroxisome proliferator-activated receptors
Xu, H. E., Lambert, M. H., Montana, V. G., Parks, D. J., Blanchard, S. G., Brown, P. J., Sternbach, D. D., Lehmann, J. M., Wisely, G. B., Willson, T. M., et al. (1999) · Molecular Cell
Peroxisome Proliferator-Activated ReceptorsProtein Structure and Dynamics
Cited by 1,169
- Verified
The promise and peril of chemical probes
Arrowsmith, C. H., Audia, J. E., Austin, C., Baell, J., Bennett, J., Blagg, J., Bountra, C., Brennan, P. E., Brown, P. J., Bunnage, M. E., et al. (2015) · Nature Chemical Biology
Click Chemistry and ApplicationsComputational Drug Discovery Methods
Cited by 839
- Verified
Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia
Grebien, F., Vedadi, M., Getlik, M., Giambruno, R., Grover, A., Avellino, R., Skucha, A., Vittori, S., Kuznetsova, E., Smil, D., et al. (2015) · Nature Chemical Biology
Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes
Cited by 284
- Verified
Discovery and Development of Potent and Selective Inhibitors of Histone Methyltransferase G9a
Sweis, R. F., Pliushchev, M., Brown, P. J., Guo, J., Li, F., Maag, D., Petros, A. M., Soni, N. B., Tse, C., Vedadi, M., et al. (2014) · ACS Medicinal Chemistry Letters
Epigenetics and DNA MethylationCancer-related gene regulation
Cited by 193
- Verified
A resource to enable chemical biology and drug discovery of WDR Proteins
Ackloo, S., Li, F., Szewczyk, M., Seitova, A., Loppnau, P., Zeng, H., Xu, J., Ahmad, S., Arnautova, Y. A., Baghaie, A., et al. (2024) · Journal of Medicinal Chemistry
Computational Drug Discovery MethodsProtein Degradation and Inhibitors
Cited by 24
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