Sznajder, Jacob I.

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

Reyfman, P. A., Walter, J. M., Joshi, N., Anekalla, K. R., McQuattie-Pimentel, A. C., Chiu, S., Fernandez, R., Akbarpour, M., Chen, C.-I., Ren, Z., et al. (2019) · American Journal of Respiratory and Critical Care Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisSingle-cell and spatial transcriptomics

Cited by 1,203

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

Misharin, A. V., Morales-Nebreda, L., Reyfman, P. A., Cuda, C. M., Walter, J. M., McQuattie-Pimentel, A. C., Chen, C.-I., Anekalla, K. R., Joshi, N., Williams, K. J. N., et al. (2017) · Journal of Experimental Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTransplantation: Methods and Outcomes

Cited by 1,133

Hypoxia-induced endocytosis of Na,K-ATPase in alveolar epithelial cells is mediated by mitochondrial reactive oxygen species and PKC-ζ

Dada, L. A., Chandel, N. S., Ridge, K. M., Pedemonte, C., Bertorello, A. M., & Sznajder, J. I. (2003) · Journal of Clinical Investigation

High Altitude and HypoxiaIon Transport and Channel Regulation

Cited by 314

The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging

McQuattie-Pimentel, A. C., Ren, Z., Joshi, N., Watanabe, S., Stoeger, T., Chi, M., Lu, Z., Sichizya, L., Aillon, R. P., Chen, C.-I., et al. (2021) · Journal of Clinical Investigation

Genetics, Aging, and Longevity in Model OrganismsImmune responses and vaccinations

Cited by 177

High CO2 Levels Cause Skeletal Muscle Atrophy via AMP-activated Kinase (AMPK), FoxO3a Protein, and Muscle-specific Ring Finger Protein 1 (MuRF1)

Jaitovich, A., Angulo, M., Lecuona, E., Dada, L. A., Welch, L. C., Cheng, Y., Gusarova, G., Ceco, E., Liu, C., Shigemura, M., et al. (2015) · Journal of Biological Chemistry

Muscle Physiology and DisordersMetabolism, Diabetes, and Cancer

Cited by 137

Metformin targets mitochondrial electron transport to reduce air-pollution-induced thrombosis

Soberanes, S., Misharin, A. V., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., et al. (2019) · Cell Metabolism

Air Quality and Health ImpactsMetabolism, Diabetes, and Cancer

Cited by 131

α1-AMP-Activated Protein Kinase Regulates Hypoxia-Induced Na,K-ATPase Endocytosis via Direct Phosphorylation of Protein Kinase Cζ

Gusarova, G. A., Dada, L. A., Kelly, A. M., Brodie, C., Witters, L. A., Chandel, N. S., & Sznajder, J. I. (2009) · Molecular and Cellular Biology

Metabolism, Diabetes, and CancerIon Transport and Channel Regulation

Cited by 118

Hyperoxia-induced Apoptosis Does Not Require Mitochondrial Reactive Oxygen Species and Is Regulated by Bcl-2 Proteins

Budinger, G. R. S., Tso, M., McClintock, D. S., Dean, D. A., Sznajder, J. I., & Chandel, N. S. (2002) · Journal of Biological Chemistry

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 95

Regulation of alveolar epithelial function by hypoxia

Zhou, G., Dada, L. A., & Sznajder, J. I. (2008) · European Respiratory Journal

Ion Transport and Channel RegulationRespiratory Support and Mechanisms

Cited by 57

Epigenetic Regulation of Muscle Phenotype and Adaptation: A Potential Role in COPD Muscle Dysfunction

Barreiro, E., & Sznajder, J. I. (2013) · Journal of Applied Physiology

Muscle Physiology and DisordersEpigenetics and DNA Methylation

Cited by 47