Lian, Christine

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

Tirosh, I., Izar, B., Prakadan, S. M., Wadsworth, M. H., Treacy, D., Trombetta, J. J., Rotem, A., Rodman, C., Lian, C., Murphy, G., et al. (2016) · Science

Single-cell and spatial transcriptomicsCancer Immunotherapy and Biomarkers

Cited by 4,944

Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma

Lian, C. G., Xu, Y., Ceol, C., Wu, F., Larson, A., Dresser, K., Xu, W., Tan, L., Hu, Y., Zhan, Q., et al. (2012) · Cell

Epigenetics and DNA MethylationChromatin Remodeling and Cancer

Cited by 789

Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer

Wu, D., Hu, D., Chen, H., Shi, G., Fetahu, I. S., Wu, F., Rabidou, K., Fang, R., Tan, L., Xu, S., et al. (2018) · Nature

Metabolism, Diabetes, and CancerEpigenetics and DNA Methylation

Cited by 477

Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3

Grebinoski, S., Zhang, Q., Cillo, A. R., Manne, S., Xiao, H., Brunazzi, E. A., Tabib, T., Cardello, C., Lian, C. G., Murphy, G. F., et al. (2022) · Nature Immunology

T-cell and B-cell ImmunologyDiabetes and associated disorders

Cited by 107

Liver stromal cells restrict macrophage maturation and stromal IL-6 limits the differentiation of cirrhosis-linked macrophages

Buonomo, E. L., Mei, S., Guinn, S. R., Leo, I. R., Peluso, M. J., Nolan, M.-A., Schildberg, F. A., Zhao, L., Lian, C., Xu, S., et al. (2022) · Journal of Hepatology

Liver physiology and pathologyLiver Disease and Transplantation

Cited by 57