Byrne, Leah C.

In Vivo–Directed Evolution of a New Adeno-Associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous

Dalkara, D., Byrne, L. C., Klimczak, R. R., Visel, M., Yin, L., Merigan, W. H., Flannery, J. G., & Schaffer, D. V. (2013) · Science Translational Medicine

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 734

In vivo genome editing improves motor function and extends survival in a mouse model of ALS

Gaj, T., Ojala, D. S., Ekman, F. K., Byrne, L. C., Limsirichai, P., & Schaffer, D. V. (2017) · Science Advances

Amyotrophic Lateral Sclerosis ResearchCRISPR and Genetic Engineering

Cited by 185

In vivo–directed evolution of adeno-associated virus in the primate retina

Byrne, L. C., Day, T. P., Visel, M., Strazzeri, J. A., Fortuny, C., Dalkara, D., Merigan, W. H., Schaffer, D. V., & Flannery, J. G. (2020) · JCI Insight

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 104

Retinoschisin gene therapy in photoreceptors, Müller glia or all retinal cells in the Rs1h−/− mouse

Byrne, L. C., Öztürk, B. E., Lee, T., Fortuny, C., Visel, M., Dalkara, D., Schaffer, D. V., & Flannery, J. G. (2014) · Gene Therapy

Retinal Development and DisordersVirus-based gene therapy research

Cited by 96

Anti-VEGF AAV2 injections: The fewer the better

Byrne, L. C. (2017) · Science Translational Medicine

Retinal Diseases and TreatmentsVirus-based gene therapy research

Cited by 2