Jansen, Aaron P.

The Transformation Suppressor Pdcd4 Is a Novel Eukaryotic Translation Initiation Factor 4A Binding Protein That Inhibits Translation

Yang, H.-S., Jansen, A. P., Komar, A. A., Zheng, X., Merrick, W. C., Costes, S., Lockett, S. J., Sonenberg, N., & Colburn, N. H. (2003) · Molecular and Cellular Biology

RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer

Cited by 494

Epidermal Expression of the Translation Inhibitor Programmed Cell Death 4 Suppresses Tumorigenesis

Jansen, A. P., Camalier, C. E., & Colburn, N. H. (2005) · Cancer Research

Cancer-related Molecular PathwaysRNA and protein synthesis mechanisms

Cited by 212

Loss of programmed cell death 4 expression marks adenoma‐carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer

Mudduluru, G., Medved, F., Grobholz, R., Jost, C., Gruber, A., Leupold, J. H., Post, S., Jansen, A., Colburn, N. H., & Allgayer, H. (2007) · Cancer

Cell death mechanisms and regulationGenetic factors in colorectal cancer

Cited by 196

A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-κB or ODC transactivation

Yang, H.-S., Jansen, A. P., Nair, R., Shibahara, K., Verma, A. K., Cmarik, J. L., & Colburn, N. H. (2001) · Oncogene

Mechanisms of cancer metastasisCancer-related Molecular Pathways

Cited by 185

Translation Inhibitor Pdcd4 Is Targeted for Degradation during Tumor Promotion

Schmid, T., Jansen, A. P., Baker, A. R., Hegamyer, G., Hagan, J. P., & Colburn, N. H. (2008) · Cancer Research

Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways

Cited by 151

Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity

Jansen, A. P., Camalier, C. E., Stark, C., & Colburn, N. H. (2004) · Molecular Cancer Therapeutics

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 132